| MAJOR | "Changing My ___" ("Fun Home" song) |
| MAJOR | "Ground Control to ___ Tom" (lyric in David Bowie's "Space Oddity") |
| MAJOR | "M" in MLS |
| MAJOR | "M*A*S*H" rank for Houlihan |
| MAJOR | "___ Crimes" ("The Closer" spin-off starring Mary McDonnell) |
| MAJOR | "___ Crimes" (TNT police series starring Mary McDonnell) |
| MAJOR | "___ League" (1989 baseball film) |
| MAJOR | "___ League" (baseball film starring Tom Berenger) |
| MAJOR | Academic concentration |
| MAJOR | Area of specialization chosen by a student at college |
| MAJOR | Army officer |
| MAJOR | Army rank |
| MAJOR | Army rank ... or a word that means "area of academic focus" |
| MAJOR | Army rank above captain |
| MAJOR | Army rank below lieutenant colonel |
| MAJOR | Army rank below lieutenant colonel...or a synonym of "important" |
| MAJOR | Army rank between captain and lieutenant colonel |
| MAJOR | Army rank under colonel |
| MAJOR | Art history or philosophy, e.g. |
| MAJOR | Base V.I.P. |
| MAJOR | Big tournament in tennis or golf |
| MAJOR | Big tourney |
| MAJOR | Big-time |
| MAJOR | Biology or English |
| MAJOR | Blair's predecessor |
| MAJOR | Business Administration or English Lit, e.g. |
| MAJOR | Captain's superior |
| MAJOR | Captain’s superior |
| MAJOR | Chemistry, journalism, or engineering, in college |
| MAJOR | College choice |
| MAJOR | College concentration |
| MAJOR | College declaration |
| MAJOR | College focus |
| MAJOR | College pick |
| MAJOR | College specialty |
| MAJOR | College student's academic focus |
| MAJOR | College student's choice |
| MAJOR | College student's concentration |
| MAJOR | College student's declaration |
| MAJOR | College student's field of study |
| MAJOR | College student's focus |
| MAJOR | College student's main area of study |
| MAJOR | College student's main subject |
| MAJOR | College student's primary field of study |
| MAJOR | College student's primary focus |
| MAJOR | College student's selection |
| MAJOR | College student's specialty subject |
| MAJOR | College study |
| MAJOR | Collegian's choice |
| MAJOR | Collegian's concentration |
| MAJOR | Collegian's field of study |
| MAJOR | Collegian's focus |
| MAJOR | Collegian's principal study |
| MAJOR | Collegian's selection |
| MAJOR | Collegiate focus |
| MAJOR | Colonel's subordinate |
| MAJOR | Concentration declared by a college student |
| MAJOR | Course of study |
| MAJOR | Declaration from a college student? |
| MAJOR | Declaration of education |
| MAJOR | Epic |
| MAJOR | Field of concentration at a university |
| MAJOR | First name, middle name, last name, and rank of a "Catch-22" character |
| MAJOR | Greater or more important |
| MAJOR | High-ranking soldier |
| MAJOR | Hoople or Houlihan |
| MAJOR | Houlihan's rank |
| MAJOR | Huge |
| MAJOR | Important |
| MAJOR | Kind of key |
| MAJOR | Kind of party |
| MAJOR | Life-and-death |
| MAJOR | Like some parties |
| MAJOR | Lowest field rank |
| MAJOR | MLB part |
| MAJOR | Main course of study |
| MAJOR | Main field of study |
| MAJOR | Main subject studied during college |
| MAJOR | Main subject studied in college |
| MAJOR | Main, most important |
| MAJOR | Military rank of Garland Briggs in "Twin Peaks" |
| MAJOR | Most part |
| MAJOR | Musical key that's not minor |
| MAJOR | Not minor |
| MAJOR | Notable |
| MAJOR | Notable, significant |
| MAJOR | Of great importance |
| MAJOR | One of four on the annual tennis calendar |
| MAJOR | One of twenty won by Roger Federer |
| MAJOR | Opposite of "minor" |
| MAJOR | Opposite of minor |
| MAJOR | Paramount |
| MAJOR | Part of MLB |
| MAJOR | Primary field of study |
| MAJOR | Primary field of study in college |
| MAJOR | Primary focus of study in college |
| MAJOR | Primary study |
| MAJOR | Principal |
| MAJOR | Prominent |
| MAJOR | Rank achieved by Jay Gatsby in "The Great Gatsby" |
| MAJOR | Rank for Tom in Bowie's "Space Oddity" |
| MAJOR | See 3-Down |
| MAJOR | See 4 Down |
| MAJOR | See 53-Across |
| MAJOR | See 8 Across |
| MAJOR | See 8-Down |
| MAJOR | Serious |
| MAJOR | Significant |
| MAJOR | Signifi-cant |
| MAJOR | Something a college junior has that a freshman usually doesn't |
| MAJOR | Something declared by a college student |
| MAJOR | Sophomore's choice |
| MAJOR | Student's declaration |
| MAJOR | Student's focus |
| MAJOR | TV's "__ Dad" |
| MAJOR | TV's"_____Dad" |
| MAJOR | Thatcher's successor |
| MAJOR | The "M" in sports' "MLB" |
| MAJOR | The "M" of "MLB" |
| MAJOR | The "M" of "MLS" and "MLB" |
| MAJOR | The French Open or Wimbledon |
| MAJOR | The M of M.L.B. |
| MAJOR | The Masters or British Open, e.g. |
| MAJOR | The Masters or the U.S. Open, in golf |
| MAJOR | The Masters, as tournaments go |
| MAJOR | The Masters, e.g. |
| MAJOR | The most popular one for college students is Business |
| MAJOR | Tom's rank in a David Bowie song |
| MAJOR | Undergraduate's declaration |
| MAJOR | University student's main area of study |
| MAJOR | Ursa follower |
| MAJOR | With 6-Across, happy-sounding thing in music |
| MAJOR | Women's studies or psychology, for some college students |
| MAJOR | Word before league or domo |
| MAJOR | ___ Domo |
| MAJOR | ___ League Baseball |
| MAJOR | ___ League Baseball (Brewers and Mariners group) |
| MAJOR | ___ League Baseball (Cubs and Reds group) |
| MAJOR | ___ League Soccer |
| MAJOR | ___ league (top sports level) |
| MAJOR | ___ medical |
| MAJOR | _____ Barbara |
| MAJOR | *"Catch-22" character |