| 100% | AMOS | 4 | "___ 'n' Andy," 1920s radio sitcom with the iconic duo which was first aired by WMAQ before going national |
| 27% | TCM | 3 | Its first airing was ''Gone With the Wind'' (1994) |
| 26% | WAKEME | 6 | "___ Up Before You Go-Go," hit song by pop duo Wham! which featured in the movie "Zoolander": 2 wds. |
| 23% | WHAM | 4 | Duo with the 1984 hit "Wake Me Up Before You Go-Go" |
| 23% | ATOM | 4 | ___ bomb, nuclear weapon which was first mentioned in the sci-fi novel "The World Set Free" by HG Wells |
| 23% | WHAM | 4 | Duo whose first US hit was "Wake Me Up Before You Go-Go" |
| 23% | REDARROWS | 9 | Name by which the Royal Air Force Aerobatic Team are known |
| 23% | ALLBLACKS | 9 | Name by which the New Zealand national rugby union team is known |
| 22% | NICKELODEON | 11 | Pay TV network which was launched as the first cable channel for children and airs "Dora the Explorer" |
| 22% | THEWILDANGELS | 13 | Biker film directed by Roger Corman which was the first film to associate Peter Fonda with Harley-Davidson motorcycles: 3 wds |
| 22% | PBS | 3 | Its first airing was "The French Chef" with Julia Child |
| 21% | VIETCONG | 8 | Name by which the National Liberation Front for South Vietnam was known during the Vietnam War |
| 21% | MARTHA | 6 | With 34-Across, Beatles song inspired by Paul's dog, on which Paul McCartney is the only credited Beatle |
| 21% | YOU | 3 | "Me Before ___," 2012 novel by Jojo Moyes which depicts the story of Louisa Clark and Will Traynor |
| 21% | ROBOT | 5 | Invention that was first mentioned in the sci-fi novel "R.U.R" by Karel Capek from which the name was derived |
| 21% | FRIENDS | 7 | Sitcom with the theme song "I'll Be There for You" |
| 21% | ASIN | 4 | "... which is the first letter of ..." |
| 21% | IKEA | 4 | Company that was the first in the U.S. to air a TV ad with a gay couple (1994) |
| 21% | INTHISECONOMY | 13 | "... with the way things are currently going?!" |
| 21% | LUGE | 4 | Winter Olympic sport which is also a small one or two person sled that rhymes with "huge" and was first played in the 1870s |
| 20% | RUGBY | 5 | ___ sevens, sport which was first contested in the 2016 Summer Olympics |
| 20% | BELLS | 5 | "Jingle ___," iconic Christmas carol that was the first song played on musical instruments in space by Gemini 6 astronauts in 1965 |
| 20% | FRASIER | 7 | Titular sitcom character who says, about an enemy, "Charm is the vicious grease with which he oils his flim-flam machine" |
| 20% | KELLY | 5 | Clarkson with the 2004 hit "Since U Been Gone" |
| 20% | EGYPTIANS | 9 | Cats were first domesticated by the ancient __ |
| 20% | MOBYDICK | 8 | Novel whose first chapter is preceded by eighty epigraphs, none of which ought to be taken as “veritable gospel cetology,” per the author |
| 20% | BETH | 4 | A hit song by Kiss, which was performed with the New York Philharmonic |
| 20% | HEART | 5 | "My ___ Will Go On," song by Celine Dion which served as the theme song to James Cameron's 1997 epic romance film "Titanic" |
| 19% | GONE | 4 | "___ with the Wind," iconic Hollywood movie that was released in 1939 |