| 100% | BABYLON | 7 | "___ 5," sci-fi drama about space that is centered around a human-run space station |
| 45% | LOST | 4 | "___ in Space," sci-fi show about space that is a futuristic take on "Swiss Family Robinson" |
| 42% | JETSONS | 7 | "The ___," animated sci-fi sitcom about space that revolves around a high-tech family who live in Orbit City |
| 42% | EXPANSE | 7 | "The ___," sci-fi drama series about space that focuses on a political conflict between Earth and other planets |
| 40% | LIFE | 4 | "Another ___," sci-fi drama series about space that follows a crew of astronauts as they investigate a mysterious alien artifact |
| 34% | TVDRAMA | 7 | Something that might be built around a police station |
| 34% | LIFEONMARS | 10 | 2008-2009 ABC sci-fi crime drama series that was a remake of a British TV series: 3 wds. |
| 34% | ACTIVITY | 8 | "Paranormal ___," 2007 supernatural horror film that is centered around camera footages in a haunted house |
| 33% | SPACE | 5 | "2001: A ___ Odyssey," 1968 sci-fi film about a voyage to Jupiter that was made by collaborating with engineers |
| 33% | EXPANSE | 7 | "The ___," sci-fi TV series starring Steven Strait that is set in a future where humans colonize the Solar System |
| 32% | GREAT | 5 | "___ News," sitcom starring Andrea Martin that is about a fictional news station |
| 31% | COMET | 5 | "Off On A ___," science fiction novel by Jules Verne about characters that are unwittingly carried off into space |
| 31% | ORPHAN | 6 | __ Black, sci-fi drama about a woman and her clones |
| 31% | PEARL | 5 | "Mama's ___," 1970 song by the Jackson 5 that is about a mama's girl |
| 31% | JURASSICWORLD | 13 | 2015 sci-fi adventure film about a theme park of cloned dinosaurs, that is the fifth highest-grossing film of all time: 2 wds. |
| 30% | SEOUL | 5 | "___ Station," 2016 Korean animated horror film directed by Yeon Sang-ho that is about a zombie epidemic |
| 30% | ROCKET | 6 | "___ Man," Elton John number that is a popular wake-up song aboard the International Space Station |
| 30% | CHERNOBYL | 9 | Historical drama TV miniseries about a nuclear disaster of April 1986 that was released in 2019 |
| 30% | FIREFLY | 7 | Sci-fi western series about space that blends space travel and outlaw adventures |
| 29% | AURA | 4 | Energy around a human being |
| 29% | OSSIPEE | 7 | Tribe whose community was centered around a lake in New Hampshire |
| 28% | GUTTER | 6 | Waterway that might be found around a house |
| 28% | SKY | 3 | "Fire in the ___," 1993 sci-fi movie centered around a man's alien abduction experience |
| 28% | HORROR | 6 | "___ Express," 1972 sci-fi film about a frozen monster that breaks free on a train |
| 28% | SNOWPIERCER | 11 | 2013 post-apocalyptic sci-fi film about a rebellion that takes place on a train |
| 28% | MONKEYS | 7 | "12 ___," 1995 sci-fi film starring Bruce Willis which is about a pandemic |
| 28% | TENORITE | 8 | Copper mineral that may be found around a volcano |
| 28% | ONEDAYATATIME | 13 | CBS sitcom about a divorced mother raising two teenaged daughters that ran from 1975 to 1984: 5 wds. |
| 28% | MIR | 3 | Space station that was deorbited in 2001 |
| 28% | SATELLITE | 9 | A space station is an artificial one |