| 100% | ARSENIC | 7 | "___ and 58-Across" (1939 play made into a movie starring Cary Grant) |
| 55% | OLDLACE | 7 | "17-Across and ___" (1939 play made into a movie directed by Frank Capra) |
| 48% | OFMICEANDMEN | 12 | Novella by 32-Across made into a 1939 film starring Lon Chaney Jr. and Burgess Meredith (4 wds.) |
| 46% | EVERYBODYS | 10 | With 44-Across, novel by 12-Across that was made into a 1988 movie starring Dennis Quaid and Jessica Lange |
| 46% | STRIPTEASE | 10 | Novel by 44-Across that was made into a movie starring Demi Moore: 2 wds. |
| 45% | STORM | 5 | "The Perfect ___" (Sebastian Junger book made into a movie starring George Clooney) |
| 45% | CHARADE | 7 | 1963 movie starring Cary Grant and Audrey Hepburn |
| 45% | MINECRAFT | 9 | Video game made into a 2025 movie with Jason Momoa and 24-Across |
| 44% | PELICAN | 7 | "The ___ Brief," novel by John Grisham which was made into a movie starring Julia Roberts |
| 44% | ATIMETO | 7 | "___ Kill," novel by John Grisham which was made into a movie starring Sandra Bullock: 3 wds. |
| 42% | JAMAICAINN | 10 | Daphne du Maurier novel made into a 1939 Hitchcock movie |
| 42% | ROSIE | 5 | Cecelia Ahern's "Love, ___" which was adapted into a movie starring Lily Collins and Sam Claflin |
| 41% | TORTILLAFLAT | 12 | Novel by 32-Across made into a 1942 film starring Spencer Tracy and Hedy Lamarr (2 wds.) |
| 40% | SUSPICION | 9 | 1941 Alfred Hitchcock thriller starring Cary Grant and Joan Fontaine as a married couple |
| 40% | THEWINDSOFWAR | 13 | Historical novel by 43-Across made into a TV miniseries starring Robert Mitchum and Ali MacGraw (4 wds.) |
| 40% | HISGIRLFRIDAY | 13 | 1940 comedy starring Cary Grant and Rosalind Russell as exes working at a newspaper: 3 wds. |
| 39% | ADAPTED | 7 | Made into a movie, say |
| 39% | ADAPTS | 6 | Makes into a movie, say |
| 39% | CHARADE | 7 | 1963 thriller comedy starring Cary Grant and 44-Across |
| 39% | COMANCHEMOON | 12 | Bestselling novel by 5-Down made into a TV miniseries starring Val Kilmer and Steve Zahn (2 wds.) |
| 38% | LESMISERABLES | 13 | Victor Hugo's novel which was also adapted into a movie starring Anne Hathaway and has a sentence with 823 words: 2 wds. |
| 38% | THEAWFULTRUTH | 13 | 1937 comedy starring Cary Grant and Irene Dunne as a couple in the midst of divorce proceedings: 3 wds. |
| 38% | BRINGINGUPBABY | 14 | 1938 comedy starring Cary Grant and Katharine Hepburn as a mismatched pair tracking down an escaped leopard: 3 wds. |
| 38% | RENT | 4 | 1996 Best Musical Tony winner made into a 2005 movie starring six of the eight original Broadway cast members |
| 38% | EMMA | 4 | Austen novel made into a movie |
| 37% | LONESOMEDOVE | 12 | Pulitzer Prize-winning novel by 5-Down made into a TV miniseries starring Robert Duvall and Tommy Lee Jones (2 wds.) |
| 37% | MYSTICRIVER | 11 | Dennis Lehane novel made into a film starring Sean Penn and Tim Robbins (2 wds.) |
| 37% | SHUTTERISLAND | 13 | Dennis Lehane novel made into a film starring Leonardo DiCaprio and Mark Ruffalo (2 wds.) |
| 37% | LIVEBYNIGHT | 11 | Dennis Lehane novel made into a film starring Ben Affleck and Elle Fanning (3 wds.) |
| 37% | THEBESTOFME | 11 | Nicholas Sparks novel made into a film starring James Marsden and Michelle Monaghan (4 wds.) |