| 100% | MEN | 3 | "___ in Black" (comic series adapted into a famous movie franchise) |
| 44% | MEN | 3 | "___ in Black," movie series starring Will Smith based on the comic book series by Lowell Cunningham |
| 42% | EVIL | 4 | "The ___ Dead" (first movie in a horror franchise soon to include a Starz series) |
| 41% | HIGHFIDELITY | 12 | 50-Across novel that was adapted into a feature film in 2000, a Broadway musical in 2006, and a TV series in 2020 (2 wds.) |
| 40% | DEAR | 4 | "___ White People" (2014 film adapted into a Netflix series) |
| 40% | GIRLBOSS | 8 | #____ (2014 Sophia Amoruso autobiography adapted into a Netflix series) |
| 40% | ODE | 3 | "___ to Billie Joe" (1967 song adapted into a movie) |
| 40% | TANK | 4 | "___ Girl" (British comic book series adapted into a film starring Lori Petty and Naomi Watts) |
| 39% | MEN | 3 | "___ in Black" (sci-fi movie franchise) |
| 39% | ONE | 3 | "___ Piece" (popular manga adapted into a live-action Netflix series) |
| 39% | EVITA | 5 | Andrew Lloyd Webber musical adapted into a movie starring Madonna |
| 39% | MORTALKOMBAT | 12 | Fighting video game adapted into a series of films: 2 wds. |
| 39% | ONE | 3 | "Ready Player ___," 2011 sci-fi novel later adapted into a movie |
| 38% | GABLE | 5 | Butler in a famous movie? |
| 38% | GONE | 4 | Gillian Flynn's thriller novel "___ Girl" which was adapted into a movie |
| 38% | SHADOWANDBONE | 13 | Fantasy trilogy by 40-Across adapted into a 2021 Netflix series (3 wds.) |
| 38% | FIFTYSHADES | 11 | Erotic trilogy whose first book is being adapted into a movie: 2 wds. |
| 38% | BOOKTHIEF | 9 | Mark Zusak's novel "The ___" which was adapted into a movie: 2 wds. |
| 38% | AIDA | 4 | Opera that was adapted into a musical that opened on Broadway in 2000 |
| 37% | HERSELF | 7 | What a famous woman may play in a movie |
| 37% | RELIEF | 6 | Comic __, humorous moments in a movie, book |
| 37% | DEMI | 4 | ___ Moore, star of the podcast "Dirty Diana" that was adapted into a drama series |
| 37% | ATIMETOKILL | 11 | 1989 legal thriller that was adapted into a movie starring Sandra Bullock: 4 wds. |
| 37% | SEED | 4 | "The Bad ___," horror novel written by William March which was adapted into a movie |
| 37% | ROOM | 4 | 2010 novel by Emma Donoghue that was adapted into a movie starring Brie Larson |
| 37% | TWO | 3 | Second in a movie series |
| 37% | WILLSMITH | 9 | Star of the "Men in Black" movie series: 2 wds. |
| 37% | NCIS | 4 | Franchise with a series set in New Orleans |
| 37% | OUTSIDERS | 9 | S.E. Hinton's coming-of-age novel "The ___" which was adapted into a movie |
| 37% | INTO | 4 | Jon Krakauer's novel "___ the Wild" which was adapted into a movie by Sean Penn |