| 100% | FALSEHOOD | 9 | "___ of the tongue leads to that of the heart": Jefferson |
| 55% | DUMBARTON | 9 | __ Oaks, conference that led to founding of the UN |
| 50% | AERIALSHOT | 10 | Type of photo that led to the "Streisand effect" |
| 50% | REDSCARE | 8 | Panic that led to the blacklisting of the Hollywood Ten |
| 50% | SETUP | 5 | Part of a joke that leads to the punch line |
| 49% | VENA | 4 | Either one of the two large veins that convey oxygen-depleted blood to the heart |
| 49% | YELLOW | 6 | Color of the road that led to the Wizard of Oz |
| 49% | ARABSPRING | 10 | Series of uprisings that led to the ouster of Hosni Mubarak |
| 48% | SACRA | 5 | Via ___, ancient Rome's main street that led from the top of the Capitoline Hill to the Colosseum |
| 47% | THEELEPHANTMAN | 14 | 1980 film that led to the creation of the Academy Award for Best Makeup |
| 46% | ERIS | 4 | Greek goddess of discord who tossed the golden apple that eventually led to the Trojan War |
| 46% | RABBITHOLE | 10 | Quick internet lookup that somehow leads to two hours of reading about the Shmoo, for example |
| 46% | COURT | 5 | Word with "ship" to refer to the course of a romantic relationship that might lead to marriage |
| 46% | JUGULAR | 7 | — vein, any one of four in the neck that return blood to the heart from the head |
| 46% | HEAT | 4 | ___ wave, climate condition leading to high temperatures that is a proposed theory for the extinction of dinosaurs |
| 46% | COLD | 4 | ___ wave, climate condition leading to freezing temperatures that is a proposed theory for the extinction of dinosaurs |
| 45% | SMOG | 4 | Fog that has combined with excessive smoke in the air, often leading to a lot of lung diseases |
| 45% | NATURALGAS | 10 | Trinidad and Tobago resource that has led to it be one of the richest western countries per capita |
| 45% | AORTA | 5 | It connects to one of the heart's four valves |
| 44% | SEA | 3 | ___ level change, condition leading to oceanic water level changes that is a proposed theory for the extinction of dinosaurs |
| 44% | PEARL | 5 | With 4 Down, site of the attack that on today's date in 1941 lead to the US entering WWII |
| 43% | CORONARY | 8 | Relating to the arteries that surround the heart |
| 43% | CARDIO | 6 | Type of exercise that gets the heart pumping |
| 43% | KORAN | 5 | Book that refers to "People of the Book" |
| 43% | NEUTRON | 7 | Uncharged elementary particle with a mass nearly equal to that of the proton |
| 43% | COLDFEET | 8 | Last-minute nerves leading to a change of heart |
| 43% | DEADIVING | 9 | *Endeavor that can lead to swimming with the fishes |
| 43% | STAIRSTEP | 9 | Part of a flight leading to the next floor |
| 43% | DLI | 3 | Roman numeral that anagrams to part of the eye |