| 100% | GOD | 3 | "___ of War," video game franchise that is based on Greek and Norse mythology |
| 44% | MARIO | 5 | "Super ___ Adventures," comic collection from Nintendo Power magazine which was based on the video game franchise of the same name |
| 43% | BROTHER | 7 | "Big ___," television reality franchise that is based on the Dutch show of the same name |
| 42% | MADDENNFL | 9 | Video game franchise that featured 15-Across on the cover of the 2011 version: 2 wds. |
| 41% | STREET | 6 | "___ Fighter," 1994 action film starring Kylie Minogue that was based on the eponymous video game series |
| 40% | INCOME | 6 | Type of tax that is based on earnings and gains |
| 37% | HALO | 4 | "___: Combat Evolved," 2001 video game that revolves around a war between humanity and an alliance of aliens |
| 37% | GOD | 3 | ___ of War (mythology-based video game franchise) |
| 36% | LUNAR | 5 | Calendar that is based on the cycles of the Moon |
| 36% | TRAIL | 5 | "The Oregon ___," the longest-running video game franchise that was co-created by Don Rawitsch |
| 36% | KANE | 4 | "The ___ Chronicles," trilogy written by Rick Riordan that is based on Egyptian mythology |
| 36% | ALIEN | 5 | Video game franchise based on a sci-fi film franchise |
| 35% | GODOFWAR | 8 | Kratos video-game series based on Greek mythology |
| 34% | RAY | 3 | 2004 musical starring Jamie Foxx that is based on the life of soul musician Charles |
| 34% | FUNNY | 5 | "___ Girl," 1968 musical starring Barbra Streisand that is based on the life of Fanny Brice |
| 34% | MORTALKOMBAT | 12 | 1995 American fantasy action film based on the video game of the same name, with characters like Liu Kang and Johnny Cage: 2 wds. |
| 34% | GLORY | 5 | "Bound for ___," 1976 musical starring David Carradine that is based on the life of Woody Guthrie |
| 34% | ERIN | 4 | "___ Brockovich," courtroom drama starring Julia Roberts that was based on the true story of an activist |
| 34% | GEARS | 5 | ___ of War (video game franchise) |
| 34% | FICTION | 7 | Gears of War is a science __ video game |
| 34% | FINAL | 5 | "___ Fantasy," one of the longest-running video game franchise that was created by Hironobu Sakaguchi |
| 33% | DAWN | 4 | "Until ___," video game that contains references of Algonquin mythology |
| 33% | BIG | 3 | "___ Hero 6: The Series," Disney series that is based on the 2014 eponymous film and stars Maya Rudolph |
| 33% | MORTAL | 6 | "___ Kombat," one of the longest-running video game franchise that was originally developed by Midway Games |
| 33% | MARIOBROS | 9 | Video game franchise with characters found at the ends of 17-, 20-, 53- and 58-Across |
| 33% | MAX | 3 | "___ Payne," 2008 mystery movie starring Mark Wahlberg which was based on a video game |
| 33% | REEK | 4 | Huge creature that went on a rampage in "Star Wars: Attack of the Clones" and was killed by the marksmanship of Jango Fett |
| 33% | PAYNE | 5 | "Max ___," video game that contains many allusions to Norse mythology |
| 33% | HALOTHREE | 9 | Sequel that was the top-selling video game of 2007 |
| 33% | DICE | 4 | Objects that are shaken and tossed in games of chance |