| 100% | MOST | 4 | "___ portrayed literary human character in film & TV," Guinness World Record awarded to Sherlock Holmes in 2012 |
| 33% | SHERLOCKHOLMES | 14 | Guinness's second-most-portrayed literary character in film, after Dracula |
| 26% | SNOWWHITE | 9 | Fairy tale character portrayed by 24-/37-Across in a 2012 film: 2 wds. |
| 26% | ILSA | 4 | Film character who says, “With the whole world crumbling, we pick this time to fall in love” |
| 26% | LONGESTMUSTACHE | 15 | 2010 Guinness world record at 11 ft. 6 in. |
| 25% | CUMBERBATCH | 11 | Benedict ___, whose birthday it is today. Shot to fame portraying the titular character in the hit series "Sherlock" |
| 25% | ROLE | 4 | Character in a film or TV show |
| 24% | NEW | 3 | Most Simultaneous U.S. Hot 100 ___ Entries, Guinness World Record set by Taylor Swift in 2021 |
| 24% | NIGEL | 5 | Bruce who played Watson in Sherlock Holmes films |
| 24% | BEN | 3 | Nickname for actor Cumberbatch who portrayed Sherlock Holmes in the BBC series "Sherlock" |
| 24% | ALROKER | 7 | He set a Guinness World Record in 2014, reporting for 34 consecutive hours |
| 24% | MELISSA | 7 | ___ Benoist, actress who portrays the titular character in the superhero TV show "Supergirl" |
| 24% | MEDALOFFREEDOM | 14 | Presidential honor awarded to 18-Across in 2012 by Barack Obama: 3 wds. |
| 24% | NOOMIRAPACE | 11 | Actress whose character went to outer space in 2012's "Prometheus": 2 wds. |
| 24% | {FIN}IAN | 8 | Character who goes to Rainbow Valley in a 1968 film musical |
| 24% | HARPER | 6 | Taye Diggs character in Best Man film, TV series |
| 23% | RAPGOD | 6 | Eminem track with the Guinness World Record for "most words in a hit single" |
| 23% | GRANT | 5 | ___ Gustin, actor who portrays the titular character in the superhero TV show "The Flash" |
| 23% | ROSTRUM | 7 | Platform used to carry a camera in film and TV |
| 23% | MARTY | 5 | ___ McFly (main character in the "Back to the Future" films) |
| 23% | JIN | 3 | Heavenly ___, Shanghai restaurant which holds the Guinness World Record for 'Highest Restaurant in a Building' |
| 23% | INSPECTORJAVERT | 15 | Literary character played in film by Charles Laughton, Anthony Perkins and Geoffrey Rush |
| 23% | JACKSPARROW | 11 | Film lead character featured in a Disney World attraction |
| 23% | POE | 3 | Edgar Allan ___, author who created the character of C. Auguste Dupin, a precursor to Sherlock Holmes |
| 23% | COOK | 4 | Peter ___, actor who played Sherlock Holmes in the 1978 British film "The Hound of the Baskervilles" |
| 23% | CORPS | 5 | US Veteran ___ and Lenovo, Guinness World Record holders for the largest toy donation in 24 hours |
| 23% | EST | 3 | Suffix in "Guinness World Records" |
| 23% | MCADAMS | 7 | Rachel —, actress who played Irene Adler in 2009 action film Sherlock Holmes |
| 23% | MARKSTRONG | 10 | Actor whose roles include Lord Blackwood in 2009 action film Sherlock Holmes |
| 23% | JUDELAW | 7 | Costar of Robert Downey, Jr. in the Sherlock Holmes films: 2 wds. |