| 100% | TOMB | 4 | "___ Raider," comic book series based on the video game that features Lara Croft |
| 59% | TEAM | 4 | "___ Fortress 2," comic series based on the video game series that features mercenaries |
| 44% | WITCHER | 7 | "The ___," 2019 TV series based on the book series by Andrzej Sapkowski which was adapted into a video game |
| 44% | CASTLEVANIA | 11 | 2017 anime-influenced TV series based on the video game series of the same name |
| 44% | DRAGONS | 7 | "Dota: ___ Blood," 2021 animated TV series based on the video game series of the same name |
| 42% | FIST | 4 | "Street Fighter: Assassin's ___," 2014 live-action TV series based on the video game series of the same name |
| 40% | STREETFIGHTER | 13 | 1994 Japanese-American action film starring Jean-Claude Van Damme, based on the video game series of the same name: 2 wds. |
| 40% | TOMB | 4 | "Lara Croft: ___ Raider" (2001 movie based on a video game) |
| 38% | MADDENNFL | 9 | Video game franchise that featured 15-Across on the cover of the 2011 version: 2 wds. |
| 37% | MODOK | 5 | 2021 animated series based on a Marvel Comics character and featuring the voices of Aimee Garcia and Ben Schwartz |
| 37% | NEEDFORSPEED | 12 | 2014 action film starring Aaron Paul, based on the car racing video game series of the same name: 3 wds. |
| 37% | TOMB | 4 | "___ Raider" (video game franchise featuring Lara Croft) |
| 36% | DONEKONG | 8 | 1981 video game that featured the first appearance of Mario |
| 35% | HALO | 4 | Paramount+ series based on a video game franchise |
| 35% | THELASTOFUS | 11 | HBO series based on a post-apocalyptic video game |
| 35% | STREET | 6 | "___ Fighter," 1994 action film starring Kylie Minogue that was based on the eponymous video game series |
| 35% | HALO | 4 | Video game series featuring the alien Covenant |
| 35% | TEKKEN | 6 | Video game series featuring Kuma the bear |
| 34% | RAIDER | 6 | Video game with the character Lara Croft: Tomb __ |
| 34% | CUJO | 4 | 1983 horror movie based on a Stephen King book and featuring a rabid dog that was set largely in one location, the Trenton family home |
| 33% | NOIRE | 5 | L.A. ___ (popular video game that centers on the detective Cole Phelps) |
| 33% | FILMADAPTATION | 14 | Movie based on a book or video game |
| 33% | DIAGNOSIS | 9 | Documentary web TV series based on The New York Times Magazine column that was released in 2019 |
| 33% | WALKING | 7 | Hit show based on a comic book, The __ Dead |
| 33% | HERLOCK | 7 | ___ Sholmes, character from the video game "Ace Attorney" who was based on Sherlock Holmes |
| 33% | STORYMODE | 9 | Video game setting that allows a player to focus on the narrative |
| 33% | YOU | 3 | "___ Don't Know Jack," 2001 game show based on the video game series of the same name |
| 33% | FANTASY | 7 | "Final ___: Legend of the Crystals," 1994 anime based on the video game series of the same name |
| 32% | ANGELINAJOLIE | 13 | "Eternals" actress who plays the video game heroine Lara Croft in two films (2 wds.) |
| 32% | MORTALKOMBAT | 12 | 1995 American fantasy action film based on the video game of the same name, with characters like Liu Kang and Johnny Cage: 2 wds. |