| 100% | MAIN | 4 | "___ Street" (Sinclair Lewis novel set in a small town in Minnesota) |
| 52% | OZARK | 5 | Netflix crime drama set in a small town in Missouri |
| 50% | SOUTHPARK | 9 | Animated Comedy Central series set in a small town in Colorado: 2 wds. |
| 49% | STATE | 5 | "___ and Main" (William H. Macy film set in a small town) |
| 49% | MAIN | 4 | "State and ___" (William H. Macy film set in a small town) |
| 45% | AMERICANRUST | 12 | Novel by 31-Across set in a declining Pennsylvania steel town (2 wds.) |
| 44% | GANTRY | 6 | Last name of Elmer in a Sinclair Lewis novel |
| 43% | THEHALFMOON | 11 | 2023 novel by 30-Across about a married couple running a bar in a small town (3 wds.) |
| 43% | AMYANDISABELLE | 14 | Elizabeth Strout novel set in the fictional town of Shirley Falls about a mother and daughter (3 wds.) |
| 42% | ADANO | 5 | "A Bell for ___" (Pulitzer-winning John Hersey novel set in an Italian town) |
| 41% | BABBITT | 7 | Novel set in the fictional town of Zenith |
| 41% | MAIN | 4 | Sinclair Lewis novel "___ Street" |
| 40% | VILLAGEVICE | 11 | Smoking or drinking in a small town? |
| 40% | SNOW | 4 | Orhan Pamuk novel set in a blizzard |
| 40% | TARA | 4 | Setting in a Mitchell novel |
| 40% | SOUTHPARK | 9 | Animated comedy series set in a Colorado town |
| 40% | COMA | 4 | 1977 best-selling novel set in a hospital |
| 39% | MURDERSANATOMY | 14 | Film about a crime in a small town, abridged? |
| 39% | LONESOMEDOVE | 12 | 1986 Pulitzer-winning novel set in a cattle drive |
| 39% | ELMERGANTRY | 11 | Sinclair Lewis novel first published in 1927 |
| 39% | NEEDFULTHINGS | 13 | Stephen King novel set in a gift shop (2 wds.) |
| 39% | DORRIT | 6 | "Little ___" (18-/41-Across novel set in a debtors' prison) |
| 39% | DUNCES | 6 | A Confederacy of __, novel set in New Orleans |
| 39% | TINKERTOY | 9 | Piece in a small construction set |
| 38% | MAINSTREET | 10 | Where to find the only stoplight in a small town, typically |
| 38% | THENICKELBOYS | 13 | Colson Whitehead novel set in a Florida reform school (3 wds.) |
| 38% | ADANO | 5 | Town in a 1944 novel |
| 38% | ADANO | 5 | Town in a war novel |
| 38% | ADANO | 5 | Town in a Hersey novel |