| 100% | AMI | 3 | "___ the only one who noticed that?": 2 wds. |
| 79% | AMI | 3 | "___ the only one who's noticed this?": 2 wds. |
| 71% | AMI | 3 | "___ the only one who missed it?": 2 wds. |
| 58% | AMI | 3 | "___ the only one...?": 2 wds. |
| 55% | AMI | 3 | "___ the only one?": 2 wds. |
| 50% | SOLEHEIR | 8 | One who gets the entire estate (2 wds.) |
| 49% | WEDINTHEWHITEHOUSE | 18 | Cleveland: The only one who __ |
| 49% | WRITEWITHBOTHHANDS | 18 | Garfield: The only one who could __ |
| 48% | IAM | 3 | "___ the one who knocks!" ("Breaking Bad" quote): 2 wds. |
| 47% | STEFFIGRAF | 10 | Tennis player who is the only player (man or woman) to win a Grand Slam and Olympic gold medal in one year: 2 wds. |
| 46% | ANNASEWELL | 10 | English novelist who published only one novel in her lifetime, "Black Beauty," which is one of the top ten best selling children's novels: 2 wds. |
| 45% | ALIAR | 5 | One who cooks up a story: 2 wds. |
| 45% | LOANSHARK | 9 | One who charges too much interest: 2 wds. |
| 44% | ARDEN | 5 | Who said "There's only one Elizabeth like me, and that's the queen" |
| 44% | KANYEWEST | 9 | One half of the rap duo who performed 11-Down: 2 wds. |
| 44% | ONEI | 4 | "You're the only ___ can trust": 2 wds. |
| 43% | ONEI | 4 | "You're the only ___ trust.": 2 wds. |
| 42% | OSCARWILDE | 10 | Irish poet and playwright who wrote only one novel "The Picture of Dorian Gray" in his lifetime: 2 wds. |
| 42% | FLATEARTHER | 11 | One who says that you're not on the ball? |
| 42% | ANI | 3 | April is the only month that has one |
| 42% | TEE | 3 | August is the only month that ends with one |
| 41% | FULLFRONTAL | 11 | The only current late-night program hosted by a woman: 2 wds. |
| 41% | GEORGEFOREMAN | 13 | Heavyweight champion who lost that title to 40-Across in 1974's famous "Rumble in the Jungle": 2 wds. |
| 41% | VIDEOGAME | 9 | Sega product, such as the 1991 one that introduced 21-/42-Across: 2 wds. |
| 41% | JIMMIEJOHNSON | 13 | The only driver in NASCAR history to win five consecutive championships: 2 wds. |
| 40% | TWEET | 5 | One of the approx. 3.2 million statements that starts with "If only Bradley's arm was longer" |
| 40% | KENGRIFFEYJR | 12 | Seattle Mariners slugger who is one of only three players in the Hall of Fame who was also a #1 overall draft pick (3 wds.) |
| 40% | SORELOSER | 9 | One who pouts after a rout (2 wds.) |
| 40% | ONTO | 4 | "___ the Next One" (Jay-Z song): 2 wds. |
| 40% | ANGELINAJOLIE | 13 | "Maleficent" actress who voices an elephant in "The One and Only Ivan" (2 wds.) |