| 100% | ITHINK | 6 | "___ We're Alone Now" (#1 hit for Tiffany): 2 wds. |
| 48% | ISIT | 4 | "___ Over Now?" (2023 #1 hit for Taylor Swift): 2 wds. |
| 47% | ONTO | 4 | "Hold ___ the Nights" (#1 hit for Richard Marx): 2 wds. |
| 47% | TEENAGEDREAM | 12 | 2010 #1 hit for Katy Perry: 2 wds. |
| 47% | PRIVATEEYES | 11 | 1981 #1 hit for Hall & Oates: 2 wds. |
| 47% | RICHGIRL | 8 | 1977 #1 hit for Hall & Oates: 2 wds. |
| 47% | AROSE | 5 | "Kiss From ___" (#1 hit for Seal): 2 wds. |
| 47% | FATHERFIGURE | 12 | 1988 #1 hit for 32-Across: 2 wds. |
| 47% | ALLFOR | 6 | "___ You" (#1 hit for Janet Jackson): 2 wds. |
| 47% | BLACKBEATLES | 12 | 2016 #1 hit for Rae Sremmurd: 2 wds. |
| 47% | JUSTDANCE | 9 | 2009 #1 hit for 43-Across: 2 wds. |
| 47% | POKERFACE | 9 | 2009 #1 hit for 43-Across: 2 wds. |
| 47% | LETIT | 5 | "___ Be" (#1 hit for the Beatles): 2 wds. |
| 47% | LOVEBITES | 9 | 1988 #1 hit for Def Leppard: 2 wds. |
| 47% | ONA | 3 | "Livin' ___ Prayer" (#1 hit for Bon Jovi): 2 wds. |
| 45% | ONTO | 4 | "Hold ___ the Nights" (1988 #1 hit for Richard Marx): 2 wds. |
| 44% | THELOCOMOTION | 13 | #1 hit for Little Eva (1962) and Grand Funk Railroad (1974): 2 wds., hyph. |
| 44% | GOTTO | 5 | "What's Love ___ Do With It" (#1 hit for Tina Turner): 2 wds. |
| 44% | LADYMARMALADE | 13 | 2001 #1 hit for Christina Aguilera, Lil' Kim, Mya, and Pink: 2 wds. |
| 44% | PONYTIME | 8 | 1961 #1 hit for 34-Across that launched a horse-riding dance: 2 wds. |
| 43% | LADYMARMALADE | 13 | #1 hit for Labelle (1975) and Christina Aguilera, Lil' Kim, Mya, and Pink (2001): 2 wds. |
| 43% | MORNINGTRAIN | 12 | 1981 #1 hit for Sheena Easton that had the subtitle "Nine to Five": 2 wds. |
| 43% | SINGLELADIES | 12 | 2008 #1 hit for Beyoncé that had the subtitle "Put a Ring on It": 2 wds. |
| 43% | ILLBE | 5 | With 33-Across, #1 hit for the Jackson 5 (1970) and Mariah Carey (1992): 2 wds. |
| 43% | HEYYA | 5 | 2003 hit for OutKast: 2 wds. |
| 42% | HIGHERLOVE | 10 | 1986 #1 hit for 30-Across, which won the Grammy for Record of the Year: 2 wds. |
| 42% | KENDRICKLAMAR | 13 | Rapper who duetted with SZA on 2024's "Luther," a #1 hit for 13 weeks: 2 wds. |
| 42% | WERE | 4 | "I Think ___ Alone Now" (1987 Tiffany hit) |
| 42% | RAGDOLL | 7 | 1964 #1 hit for the Four Seasons (2 wds.) |
| 41% | THANKU | 6 | "Grateful" hit for Alanis Morissette: 2 wds. |