| 100% | DEAR | 4 | "___ White People" (2014 film adapted into a Netflix series) |
| 64% | GIRLBOSS | 8 | #____ (2014 Sophia Amoruso autobiography adapted into a Netflix series) |
| 54% | ONE | 3 | "___ Piece" (popular manga adapted into a live-action Netflix series) |
| 54% | MORTALKOMBAT | 12 | Fighting video game adapted into a series of films: 2 wds. |
| 53% | SHADOWANDBONE | 13 | Fantasy trilogy by 40-Across adapted into a 2021 Netflix series (3 wds.) |
| 53% | CHERYLSTRAYED | 13 | American novelist whose memoir "Wild" was adapted into a 2014 film: 2 wds. |
| 52% | TOALLTHEBOYS | 12 | With 32-Across, 2014 romance novel adapted into a 2018 Netflix film: 4 wds. |
| 50% | TWILIGHT | 8 | 2005 novel by Stephenie Meyer featuring vampires that was adapted into a film series starring Robert Pattinson |
| 48% | HANDMAIDSTALE | 13 | Margaret Atwood's dystopian novel, "The ___" which has been adapted into a film, an opera and a TV series: 2 wds. |
| 46% | NAME | 4 | "Spell My ___ with an S," sci-fi short story by Isaac Asimov that was adapted into a 2014 short film directed by Samuel Ali |
| 46% | HIGHFIDELITY | 12 | 50-Across novel that was adapted into a feature film in 2000, a Broadway musical in 2006, and a TV series in 2020 (2 wds.) |
| 45% | NEVERLETMEGO | 12 | 2005 dystopian novel adapted into a 2010 film |
| 45% | THEHATEUGIVE | 12 | Angie Thomas best-seller adapted into a 2018 film |
| 45% | DUNE | 4 | Sci-fi novel adapted into a hit 2021 film |
| 45% | THECLIENT | 9 | John Grisham novel adapted into a Susan Sarandon film |
| 44% | LIFEOFPI | 8 | Yann Martel book, adapted into a film and a play |
| 43% | ALCOTT | 6 | Author whose work will soon be adapted into a Gerwig film |
| 43% | ONE | 3 | “___ Night in Miami” (Kemp Powers play adapted into a 2020 film) |
| 43% | OSAGE | 5 | “August: ___ County” (Pulitzer Prize-winning play adapted into a 2013 film) |
| 43% | TEX | 3 | S.E. Hinton novel adapted into a 1982 film starring Matt Dillon |
| 42% | MILE | 4 | "The Green ___" (Stephen King serial novel adapted into a film starring Tom Hanks) |
| 42% | JAYASHER | 8 | Author whose book "Thirteen Reasons Why" was adapted into a Netflix show of the same name: 2 wds. |
| 42% | JERSEYBOYS | 10 | Hit 2005 Broadway musical made into a 2014 film |
| 42% | SUSANNAKAYSEN | 13 | American author whose memoir "Girl, Interrupted" was adapted into a 1999 film: 2 wds. |
| 42% | SOPHIESCHOICE | 13 | 1979 novel by 47-Across adapted into a film starring 30-Across (2 wds.) |
| 42% | LION | 4 | "Paper ___" (George Plimpton book about pro football adapted into a film starring Alan Alda) |
| 42% | ROAD | 4 | "The ___," 2006 novel by Cormac McCarthy that was adapted into a 2009 survival film |
| 42% | GOD | 3 | "Child of ___," 1973 novel by Cormac McCarthy that was adapted into a 2013 film |
| 42% | OUTER | 5 | "___ Dark," 1968 novel by Cormac McCarthy that was adapted into a 2009 short film |
| 41% | GONEGIRL | 8 | Gillian Flynn thriller novel made into a hit 2014 film |