| 100% | AHABS | 5 | "___ Wife" (bestselling novel inspired by "Moby-Dick") |
| 100% | AHABS | 5 | "___ Wife" (1999 bestselling novel inspired by "Moby-Dick") |
| 57% | EASTOFEDEN | 10 | Novel inspired by Cain and Abel |
| 53% | THEPEARL | 8 | Steinbeck novel inspired by a Mexican folk tale |
| 53% | ARMADA | 6 | Ernest Cline novel inspired by "The Last Starfighter" |
| 50% | DEMONCOPPERHEAD | 15 | Pulitzer-winning Barbara Kingsolver novel inspired by a Charles Dickens work |
| 50% | TIMETRAVELERS | 13 | "The ___ Wife," bestselling debut novel by Audrey Niffenegger published in 2003 about a man who moves through time and his wife: 2 wds. |
| 49% | MRSFLETCHER | 11 | 2017 bestselling novel by 37-Across (2 wds.) |
| 49% | EVERYBREATH | 11 | 2018 bestselling novel by 35-Across (2 wds.) |
| 49% | THENOTEBOOK | 11 | 1996 bestselling novel by 35-Across (2 wds.) |
| 49% | THEDUTCHHOUSE | 13 | 2019 bestselling novel by 28-Across (3 wds.) |
| 48% | THEBEACHCLUB | 12 | Bestselling novel by Elin Hilderbrand featuring a Nantucket resort (3 wds.) |
| 48% | ANCIENT | 7 | "Seven ___ Wonders," bestselling novel by Australian author Matthew Reilly |
| 48% | STARBUCKS | 9 | Coffeehouse chain with a siren logo, whose name was inspired by Melville's best friend in "Moby Dick" |
| 48% | THEMAD{HAT}TER | 14 | Chick Corea album inspired by a Lewis Carroll novel |
| 48% | LOLITA | 6 | Lana Del Rey song inspired by a Nabokov novel |
| 48% | SLAYRIDE | 8 | 1973 novel by Dick Francis |
| 48% | PROOF | 5 | 1984 novel by Dick Francis |
| 48% | NERVE | 5 | 1964 novel by Dick Francis |
| 48% | BONECRACK | 9 | 1971 novel by Dick Francis |
| 48% | DEADCERT | 8 | 1962 novel by Dick Francis |
| 48% | TWICESHY | 8 | 1981 novel by Dick Francis |
| 48% | SHATTERED | 9 | 2000 novel by Dick Francis |
| 48% | LONGSHOT | 8 | 1990 novel by Dick Francis |
| 48% | ODDS | 4 | 1965 novel by Dick Francis |
| 48% | FORKICKS | 8 | 1965 novel by Dick Francis |
| 48% | ENQUIRY | 7 | 1969 novel by Dick Francis |
| 48% | TWICE | 5 | 1981 novel by Dick Francis |