| 100% | GIRL | 4 | "___ With a Pearl Earring" (Tracy Chevalier novel about a Vermeer painting) |
| 62% | VERMEER | 7 | Dutch painter featured in Tracy Chevalier's novel "Girl with a Pearl Earring" |
| 53% | GIRL | 4 | Vermeer's "___ With a Pearl Earring" |
| 52% | CHEVALIER | 9 | Tracy __ wrote Girl with a Pearl Earring |
| 49% | EARRING | 7 | Girl With a Pearl __, iconic painting by Vermeer |
| 49% | EARRING | 7 | Girl with a Pearl __, Vermeer oil painting |
| 48% | EARRING | 7 | Vermeer painting, Girl With a Pearl __ |
| 47% | EARRING | 7 | Vermeer painted a girl with a pearl one |
| 45% | COLINFIRTH | 10 | "The King's Speech" actor who played painter Johannes Vermeer in "Girl With a Pearl Earring": 2 wds. |
| 45% | EARRING | 7 | Jan Vermeer painted a famous Girl with a Pearl one |
| 44% | GIRL | 4 | "___ With a Pearl Earring" |
| 44% | COLINFIRTH | 10 | "The King's Speech" actor who plays Dutch painter Johannes Vermeer in the film "Girl with a Pearl Earring" (2 wds.) |
| 43% | EARRING | 7 | "Girl with a Pearl ___," an oil painting by Dutch painter Johannes Vermeer which is housed in the Mauritshuis, The Hague |
| 42% | VERMEER | 7 | "Girl With a Pearl Earring" painter |
| 42% | VERMEER | 7 | Girl With a Pearl Earring painter |
| 41% | VERMEER | 7 | Dutch painter of Girl With a Pearl Earring |
| 39% | CARRIE | 6 | Horror novel about a girl with telekinetic powers |
| 39% | DEENIE | 6 | Judy Blume novel about a girl with scoliosis |
| 39% | APPLES | 6 | With 51-Across, 2021 Liane Moriarty novel about a matriarch who mysteriously disappears |
| 39% | SMILE | 5 | Raina Telgemeier graphic novel about a girl with braces |
| 39% | GIVER | 5 | Dystopian 1993 novel about a colorless world, with "The" |
| 39% | IDIOT | 5 | Dostoyevsky novel about a "positively beautiful man," with "The" |
| 38% | INSOMNIA | 8 | Stephen King novel about a man with a sleep disorder |
| 38% | LEAKHOUSE | 9 | Charles Dickens novel about a residence with constant plumbing problems? |
| 38% | WHATALICE | 9 | With 19-Across, 2009 Liane Moriarty novel about a mother who develops amnesia: 2 wds. |
| 37% | AFTER | 5 | With 29-Across, 43-Across novel about a family coping with a devastating loss |
| 37% | MARGARETTOWN | 12 | Novel by 44-Across about a woman with multiple personalities |
| 36% | SMILE | 5 | Graphic novel by Raina Telgemeier about a girl with braces |
| 36% | HELLOSTRANGER | 13 | Katherine Center novel about a portrait artist who is diagnosed with face blindness (2 wds.) |
| 36% | WHATYOUWISHFOR | 14 | Katherine Center novel about a school librarian and her relationship with the principal (4 wds.) |