| 100% | TINAFEY | 7 | "30 Rock" star who was awarded the Mark Twain Prize in 2010: 2 wds. |
| 71% | RICHARDPRYOR | 12 | "Silver Streak" star who was awarded the very first Mark Twain Prize for American Humor in 1998: 2 wds. |
| 70% | JAYLENO | 7 | Former "Tonight Show" host who was awarded the Mark Twain Prize in 2014: 2 wds. |
| 70% | CAROLBURNETT | 12 | Comedian and variety show host who was awarded the Mark Twain Prize in 2013: 2 wds. |
| 61% | DAVECHAPPELLE | 13 | "A Star Is Born" actor who won the Mark Twain Prize in 2019: 2 wds. |
| 60% | LORNEMICHAELS | 13 | "Saturday Night Live" creator who was awarded the Mark Twain Prize for American Humor (2 wds.) |
| 59% | EDDIEMURPHY | 11 | Former "Saturday Night Live" regular who was awarded the Mark Twain Prize for American Humor (2 wds.) |
| 59% | WILLFERRELL | 11 | Former "Saturday Night Live" regular who was awarded the Mark Twain Prize for American Humor (2 wds.) |
| 57% | CONAN | 5 | O’Brien who was awarded the Mark Twain Prize for American Humor, in 2025 |
| 53% | LINUSPAULING | 12 | American chemist who was awarded the Nobel Peace Prize in 1962: 2 wds. |
| 52% | TONIMORRISON | 12 | "Beloved" novelist who was awarded the Nobel Prize in Literature in the year 1993: 2 wds. |
| 50% | ADAMSANDLER | 11 | "Grown Ups" actor who won the Mark Twain Prize in 2023: 2 wds. |
| 50% | MOTHERTERESA | 12 | Albanian-Indian catholic nun who was awarded the Nobel Peace Prize in 1979: 2 wds. |
| 50% | BOBDYLAN | 8 | Singer/songwriter who was awarded the 2016 Nobel Prize in Literature (2 wds.) |
| 49% | NELSONMANDELA | 13 | South African anti-apartheid revolutionary who was awarded the Nobel Peace Prize in 1962: 2 wds. |
| 48% | LYNDONJOHNSON | 13 | U.S. president who was awarded the Silver Star in WWII by General MacArthur (2 wds.) |
| 48% | EDDIEMURPHY | 11 | "The Nutty Professor" actor and "SNL" star who won the Mark Twain Prize for American Humor in 2015: 2 wds. |
| 48% | BARACKOBAMA | 11 | 44th President of the U.S. who was awarded the Nobel Peace Prize in 2009: 2 wds. |
| 48% | WOODROWWILSON | 13 | 28th President of the U.S. who was awarded the Nobel Peace Prize in 1919: 2 wds. |
| 48% | JIMMYCARTER | 11 | 39th President of the U.S. who was awarded the Nobel Peace Prize in 2002: 2 wds. |
| 48% | WILLFERRELL | 11 | "Elf" actor and "Saturday Night Live" star who won the Mark Twain Prize for American Humor in 2011: 2 wds. |
| 48% | LORNEMICHAELS | 13 | "SNL" producer who won the Mark Twain Prize for American Humor in 2004: 2 wds. |
| 47% | BILLCOSBY | 9 | Comedian who was awarded the Spingarn Medal in 1985: 2 wds. |
| 47% | LENAHORNE | 9 | Jazz singer who was awarded the Spingarn Medal in 1983: 2 wds. |
| 46% | ROSAPARKS | 9 | Civil rights leader who was awarded the NAACP's Spingarn Medal in 1979: 2 wds. |
| 46% | JOHNLEWIS | 9 | Politician and civil rights leader who was awarded the Spingarn Medal in 2002: 2 wds. |
| 45% | ITZHAKPERLMAN | 13 | Tel Aviv-born violinist who was awarded the Presidential Medal of Freedom in 2015: 2 wds. |
| 45% | MRT | 3 | Action star who was on "Dancing With the Stars" in 2017: 2 wds. |
| 45% | ROBINWRIGHT | 11 | "House of Cards" star who was nominated for the 2017 Emmy Award for Outstanding Lead Actress in a Drama Series (2 wds.) |
| 44% | KERIRUSSELL | 11 | "The Americans" star who was nominated for the 2017 Emmy Award for Outstanding Lead Actress in a Drama Series (2 wds.) |