| 100% | ROMCOMS | 7 | "50 First Dates" and "27 Dresses," for two |
| 56% | SANDLER | 7 | Adam, star of 50 First Dates and The Waterboy |
| 55% | BARRYMORE | 9 | She starred in 50 First Dates and Charlie's Angels |
| 50% | OURTIME | 7 | Dating site for singles 50 and older |
| 49% | GEARS | 5 | First and reverse, for two |
| 42% | RITEOFPASSAGE | 13 | First date, for instance |
| 41% | SANDLER | 7 | Actor Adam known for Happy Gilmore, 50 First Dates |
| 40% | KERMIT | 6 | Character whom Jim Henson first modeled with a turquoise coat and two half-ping-pong balls for eyes |
| 40% | REDALGAE | 8 | Foodies' nori and dulse, for two |
| 40% | MEUM | 4 | First word in Greek for 'what is mine and what is thine' |
| 40% | BARRYMORE | 9 | Drew, actress who went on 50 First Dates in 2004 |
| 39% | STANMUSIAL | 10 | St. Louis Cardinals slugger who is one of four players named MLB MVP for two different fielding positions (outfield and first base) (2 wds.) |
| 39% | ADVENT | 6 | & 18D First day of the liturgical year in Western Christianity, falling on any date between November 27 and December 3 |
| 39% | ASIA | 4 | Locale for two Summer Olympics to date |
| 39% | BARTOK | 6 | "Sonata for Two Pianos and Percussion" composer |
| 39% | MEAN | 4 | Two, for one and three? |
| 37% | RALPHWALDO | 10 | First two of an essayist and poet |
| 37% | EDEN | 4 | First garden site for Adam and Eve |
| 37% | JJABRAMS | 8 | Two-time 27-Across winner for Lost |
| 37% | FACTORS | 7 | Two and one, for two |
| 37% | IAM | 3 | First two words of "Green Eggs and Ham" |
| 37% | ROM | 3 | ___-com (genre for "50 First Dates") |
| 37% | RAPSTARS | 8 | Lil' Kim and Lil Wayne, for two |
| 36% | TRISECT | 7 | Cut for yourself and two friends |
| 36% | DREW | 4 | "50 First Dates" actress Barrymore |
| 36% | DREW | 4 | "50 First Dates" star, Barrymore |
| 36% | DREW | 4 | "50 First Dates" actress ___ Barrymore |
| 36% | LIVINGPINTPINTERS | 17 | Place for a bed and dresser |
| 36% | AARP | 4 | Org. for people 50 and over |