| 100% | DAD | 3 | "American ___!" (Fox animated sitcom) |
| 88% | THESIMPSONS | 11 | Fox animated sitcom now in its 30th season: 2 wds. |
| 84% | THE | 3 | American animated sitcom "___ Simpsons" |
| 82% | BOBSBURGERS | 11 | Animated sitcom that premiered on Fox in 2011 (2 wds.) |
| 81% | THESIMPSONS | 11 | Fox animated sitcom in which 17-Across voices the recurring character Fat Tony: 2 wds. |
| 79% | DAD | 3 | Animated sitcom “American —!” |
| 77% | AMERICAN | 8 | "___ Dad!," animated sitcom that moved from Fox to TBS in 2014 |
| 77% | FAMILYGUY | 9 | Animated Fox sitcom about the dysfunctional Griffins: 2 wds. |
| 75% | BOBSBURGERS | 11 | Fox animated sitcom that once featured the voice of "Mad Men" star Jon Hamm as a toilet (2 wds.) |
| 74% | AMERICANDAD | 11 | American adult animated sitcom featuring Roger Smith which is running its 15th season: 2 wds. |
| 71% | FAMILY | 6 | American animated sitcom "___ Guy" featuring the Griffins which is in its 16th season |
| 68% | DAD | 3 | "American ___!" (Seth MacFarlane animated sitcom) |
| 64% | AMERICANDAD | 11 | Animated Seth MacFarlane sitcom |
| 64% | BIG | 3 | “___ Mouth,” Netflix animated sitcom |
| 64% | SIMPSON | 7 | Animated sitcom family name |
| 63% | GUY | 3 | "Family ___," American animated sitcom created by Seth MacFarlane |
| 63% | FAMILYGUY | 9 | Animated sitcom about the Griffins |
| 62% | GUY | 3 | "Family ___," animated sitcom |
| 62% | DAD | 3 | "American ___!," animated sitcom in which Andy Samberg voiced Ricky the Raptor |
| 61% | FAMILYGUY | 9 | Animated sitcom about the Griffin family |
| 61% | TUCAANDBERTIE | 13 | Animated sitcom with a toucan protagonist |
| 61% | MARTIN | 6 | 1990's Fox sitcom |
| 61% | FUTURAMA | 8 | Animated sci-fi sitcom following Philip J. Fry that moved from Fox to Comedy Central, and now streams on Hulu |
| 60% | ROC | 3 | Fox sitcom |
| 60% | FUTURAMA | 8 | Animated sitcom set in the 31st century |
| 59% | PJS | 3 | "The ___" (1999-2001 animated sitcom) |
| 59% | RICK | 4 | "___ and Morty," adult animated sitcom |
| 59% | BIG | 3 | Netflix's animated sitcom, "___ Mouth" |
| 59% | MORTY | 5 | "Rick and ___" (adult animated sitcom) |
| 59% | THESIMPSONS | 11 | American animated sitcom which is running its 29th season making it the longest running TV series with 629 episodes: 2 wds. |