| 100% | JOHNORTIZ | 9 | "American Fiction" actor who plays a police detective on 49-Across (2 wds.) |
| 70% | DAVIDSOUL | 9 | Actor who played a police detective in Southern California on "Starsky & Hutch" (2 wds.) |
| 69% | VINCEVAUGHN | 11 | "Wedding Crashers" actor who plays a former police detective who now inspects restaurants on 49-Across (2 wds.) |
| 60% | JAMESBROLIN | 11 | Actor who played a physician on 28-Across: 2 wds. |
| 60% | MIKECONNORS | 11 | Actor who played a private detective in Los Angeles on "Mannix" (2 wds.) |
| 60% | PETERFALK | 9 | Actor who played a homicide detective in Los Angeles on "Columbo" (2 wds.) |
| 58% | JAMESGARNER | 11 | Actor who played a private detective in Los Angeles on "The Rockford Files" (2 wds.) |
| 57% | CHARLIEDAY | 10 | "It's Always Sunny in Philadelphia" actor who plays a detective in 15-Across: 2 wds. |
| 55% | BRYANCRANSTON | 13 | "Breaking Bad" actor who plays a judge on 54-Across (2 wds.) |
| 54% | MRT | 3 | Actor who played B.A. Baracus on "The A-Team": 2 wds. |
| 54% | PAULBETTANY | 11 | Actor who plays a powerful android in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 53% | DANNYMCBRIDE | 12 | "Vice Principals" actor who played a former pro baseball player on "Eastbound & Down": 2 wds. |
| 53% | TEDDANSON | 9 | "The Good Place" actor who played a former pro baseball player on "Cheers": 2 wds. |
| 53% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |
| 53% | MATTLEBLANC | 11 | "Friends" actor who plays Adam Burns on "Man With a Plan": 2 wds. |
| 53% | MICHAELEALY | 11 | "Barbershop" actor who plays Detective Miles Hoffman on "Stumptown": 2 wds. |
| 53% | MRT | 3 | Actor who played B.A. on "The A-Team": 2 wds. |
| 53% | JEREMYSISTO | 11 | Actor who played Detective Cyrus Lupo for three seasons on "Law & Order": 2 wds. |
| 53% | JERRYORBACH | 11 | Actor who played Detective Lennie Briscoe for 12 seasons on "Law & Order": 2 wds. |
| 53% | JERRYSTILLER | 12 | Jewish actor who played Italian American Frank Costanza on "Seinfeld": 2 wds. |
| 53% | PETERFALK | 9 | Jewish actor who played Italian American Lieutenant Columbo on "Columbo": 2 wds. |
| 53% | WILLIAMSHATNER | 14 | "Star Trek" star who played a murderous actor on "Columbo": 2 wds. |
| 52% | DANNYBONADUCE | 13 | Actor who played a guitar-playing sibling on "The Partridge Family" (2 wds.) |
| 52% | TONYDANZA | 9 | "The Good Cop" actor who played a former pro baseball player on "Who's the Boss?": 2 wds. |
| 52% | ROBERTCARLYLE | 13 | "The Full Monty" actor who plays Rumplestiltskin on "Once Upon a Time": 2 wds. |
| 52% | STEVEZAHN | 9 | "Treme" actor who plays Mark Mossbacher on 49-Across (2 wds.) |
| 52% | BRIANGERAGHTY | 13 | "Chicago Med" and "Chicago Fire" actor who plays a long-haul trucker on 1-Across/65-Across (2 wds.) |
| 52% | ROBERTDUVALL | 12 | Oscar-winning actor who played a man in love with a tiny doll on "The Twilight Zone": 2 wds. |
| 52% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 52% | ANDREWLINCOLN | 13 | British actor who plays American Rick Grimes on AMC's "The Walking Dead": 2 wds. |