| 100% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character, 46-Across, on a Netflix miniseries (2 wds.) |
| 71% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character in Netflix's "Ratched": 2 wds. |
| 63% | LILYCOLLINS | 11 | Actress who plays the title character on 46-Across (2 wds.) |
| 62% | CAMILLERAZAT | 12 | Actress who plays the title character's new friend on 46-Across (2 wds.) |
| 61% | BROOKESHIELDS | 13 | "The Blue Lagoon" actress who played the title character on 46-Across (2 wds.) |
| 59% | TAISSAFARMIGA | 13 | "American Horror Story" actress who plays the naive Gladys Russell on 17-Across: 2 wds. |
| 59% | BARBARABARRIE | 13 | "Breaking Away" actress who played the title character's Nana on 46-Across (2 wds.) |
| 58% | SARAHPAULSON | 12 | "American Horror Story" actress who plays Alice on the Hulu miniseries "Mrs. America" (2 wds.) |
| 57% | LINDALAVIN | 10 | Actress who played the title character on the sitcom "Alice": 2 wds. |
| 56% | LOUISAHARLAND | 13 | "Derry Girls" actress who plays the title character on 44-Across (2 wds.) |
| 56% | EDIEFALCO | 9 | "The Sopranos" actress who played the title character on "Nurse Jackie": 2 wds. |
| 53% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 53% | SARAHPAULSON | 12 | "American Horror Story" actress who won the 2024 Best Leading Actress in a Play Tony for "Appropriate": 2 wds. |
| 53% | RACHELMCADAMS | 13 | "Doctor Strange" actress who plays the title character's mom in 33-/49-Across: 2 wds. |
| 51% | UZOADUBA | 8 | "In Treatment" actress who plays a detective on the Netflix series "The Residence": 2 wds. |
| 51% | MARGOTROBBIE | 12 | "Babylon" actress who plays the title character in "Barbie": 2 wds. |
| 51% | AUNJANUEELLIS | 13 | "Quantico" actress who plays Sharone Salaam on the Netflix miniseries "When They See Us": 2 wds. |
| 51% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 51% | KENNEDYMCMANN | 13 | Actress who plays the title role on "Nancy Drew": 2 wds. |
| 50% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" star who played the title character of 28-Across in a 2015 movie: 2 wds. |
| 50% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |
| 50% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 49% | TOMHIDDLESTON | 13 | "Kong: Skull Island" star who plays the title character on "Loki": 2 wds. |
| 49% | DONJOHNSON | 10 | "Miami Vice" actor who played the title character on 40-Across (2 wds.) |
| 49% | FRANCESCONROY | 13 | "Six Feet Under" actress who played Myrtle Snow on "American Horror Story: Coven": 2 wds. |
| 49% | ANGELABASSETT | 13 | "Waiting to Exhale" actress who played Marie Laveau on "American Horror Story: Coven": 2 wds. |
| 49% | REBECCABREEDS | 13 | "Pretty Little Liars" actress who plays the title FBI agent on 34-Across (2 wds.) |
| 48% | CHERYLHINES | 11 | Actress who plays the main character's ex-wife on "Curb Your Enthusiasm": 2 wds. |
| 48% | ALLISONJANNEY | 13 | Actress who plays Bonnie, the title mom on "Mom": 2 wds. |
| 47% | LANAPARRILLA | 12 | "Spin City" actress who plays the Evil Queen on "Once Upon a Time": 2 wds. |