| 100% | CHARLIESHEEN | 12 | "Anger Management" actor who played Phoebe's sailor boyfriend on "Friends": 2 wds. |
| 64% | BENSTILLER | 10 | "Zoolander" actor who played Rachel's screaming boyfriend on "Friends": 2 wds. |
| 64% | JONFAVREAU | 10 | "Iron Man" actor who played Monica's millionaire boyfriend on "Friends": 2 wds. |
| 62% | BOBBALABAN | 10 | "The Monuments Men" actor who played Phoebe's father, Frank Buffay, Sr., on "Friends": 2 wds. |
| 57% | SETHROGEN | 9 | "The Studio" actor who plays Sylvia's friend Will on "Platonic": 2 wds. |
| 53% | MICHAELONTKEAN | 14 | "Slap Shot" actor who played Sheriff Harry S. Truman on "Twin Peaks": 2 wds. |
| 52% | BOBDENVER | 9 | Actor who played Gilligan on "Gilligan's Island": 2 wds. |
| 51% | RONLEIBMAN | 10 | "Norma Rae" actor who played Rachel's father, Dr. Leonard Green, on "Friends": 2 wds. |
| 51% | RICHARDSCHIFF | 13 | Actor who plays Shaun's mentor Aaron Glassman on 15-Across: 2 wds. |
| 51% | DAVIDSCHWIMMER | 14 | Actor who played paleontology professor Ross Geller on "Friends": 2 wds. |
| 51% | DEANCAIN | 8 | Actor who played Superman on TV's "Lois & Clark": 2 wds. |
| 51% | PIERCEBROSNAN | 13 | Actor who played Miranda's boyfriend Stu in "Mrs. Doubtfire": 2 wds. |
| 51% | JIMBACKUS | 9 | Actor who played Thurston Howell III on "Gilligan's Island": 2 wds. |
| 50% | RYANGOSLING | 11 | "Gangster Squad" actor who played Hercules on TV's "Young Hercules": 2 wds. |
| 50% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |
| 50% | MADSMIKKELSEN | 13 | "Casino Royale" actor who plays Hannibal Lecter on NBC's "Hannibal": 2 wds. |
| 50% | BLAKEANDERSON | 13 | "Workaholics" actor who plays one of Keef's roommates on "Woke": 2 wds. |
| 50% | TOMSTURRIDGE | 12 | "Velvet Buzzsaw" actor who plays Dream on Netflix's "The Sandman": 2 wds. |
| 50% | EDMUNDGWENN | 11 | Actor who played Kris Kringle in 1947's "Miracle on 34th Street": 2 wds. |
| 50% | MATTLEBLANC | 11 | "Friends" actor who plays Adam Burns on "Man With a Plan": 2 wds. |
| 50% | JOSHUAJACKSON | 13 | Actor who played Pacey on the 1998-2003 teen drama "Dawson's Creek": 2 wds. |
| 49% | JEFFREYTAMBOR | 13 | "Transparent" actor who played Michael Bluth's father George on "Arrested Development": 2 wds. |
| 49% | MARTINFREEMAN | 13 | "The Hobbit" actor who plays Dr. Watson on the BBC's "Sherlock": 2 wds. |
| 49% | RICORODRIGUEZ | 13 | Actor who plays Manny Delgado, Gloria's son and Jay's stepson, on "Modern Family": 2 wds. |
| 49% | HUGHDANCY | 9 | "Confessions of a Shopaholic" actor who plays Will Graham on NBC's "Hannibal": 2 wds. |
| 49% | ANDREWLINCOLN | 13 | British actor who plays American Rick Grimes on AMC's "The Walking Dead": 2 wds. |
| 49% | CLANCYBROWN | 11 | "The Shawshank Redemption" actor who plays Rich Brink on Amazon's "Gen V": 2 wds. |
| 49% | ERICWINTER | 10 | "The Mentalist" actor who plays Sergeant Tim Bradford on ABC's "The Rookie": 2 wds. |
| 49% | SAMNEILL | 8 | "Jurassic Park" actor who plays Stan Delaney on Peacock's "Apples Never Fall": 2 wds. |
| 48% | CARROLLOCONNOR | 14 | Actor who played Archie on 16-Across: 2 wds. |