| 100% | PAULRUDD | 8 | "Ant-Man" and 15-Across, 22-Across, and 37-Across actor who turns 50 on April 6 (2 wds.) |
| 57% | LENCARIOU | 9 | 15-Across, 33-Across, and "Blue Bloods" actor who turned 85 years old on September 30, 2024 (2 wds.) |
| 53% | ALPACINO | 8 | Emmy-, Golden Globe-, Oscar-, and Tony-winning actor who turns 80 on April 25 (2 wds.) |
| 52% | DANIELCRAIG | 11 | "Skyfall" actor who turned 50 on March 2, 2018 (2 wds.) |
| 51% | PAULGIAMATTI | 12 | "Cinderella Man" and "Sideways" actor who turned down the role of Michael Scott on "The Office": 2 wds. |
| 51% | BILLYIDOL | 9 | 15-Across, 21-Across, and 34-Across singer who turns 65 on November 30 (2 wds.) |
| 49% | PATTONOSWALT | 12 | Comedian/actor of 14-Across and 29-Across who turned 50 on January 27, 2019 (2 wds.) |
| 48% | TINAFEY | 7 | Multi-award-winning comic, actor, writer, and producer who turned 50 on May 18, 2020 (2 wds.) |
| 48% | SHAWNCARTER | 11 | 18-Across and 29-Across rapper who turns 50 on December 4, 2019 (2 wds.) |
| 48% | MARIOLOPEZ | 10 | 16-Across and 34-Across star who turned 50 on October 10, 2023 (2 wds.) |
| 48% | HUGHJACKMAN | 11 | "The Greatest Showman" actor who turns 50 on October 12, 2018 (2 wds.) |
| 48% | HILARYSWANK | 11 | "Million Dollar Baby," 19-Across, and 34-Across actress who turned 50 years old on July 30, 2024 (2 wds.) |
| 47% | LLCOOLJ | 7 | Actor and rapper who turned 50 on January 14, 2018 (3 wds.) |
| 47% | VINDIESEL | 9 | "The Fate of the Furious" actor who turned 50 on July 18, 2017 (2 wds.) |
| 47% | DAVIDMCCALLUM | 13 | Actor who currently plays 15-Across and once played 50-Across: 2 wds. |
| 47% | ASHTONKUTCHER | 13 | Actor who replaced Charlie Sheen on "Two and a Half Men": 2 wds. |
| 46% | JAMIEFOXX | 9 | "Ray" Best Actor Oscar winner who turns 50 on December 13, 2017 (2 wds.) |
| 46% | ELIZABETHBANKS | 14 | 16-Across, 34-Across, and "Cocaine Bear" actress and filmmaker who turns 50 years old on February 10, 2024 (2 wds.) |
| 46% | REDDFOXX | 8 | Actor who starred on "Sanford and Son," a sitcom developed by Norman Lear (who turns 100 today): 2 wds. |
| 45% | NATASHALYONNE | 13 | "Orange Is the New Black," 24-Across, and 39-Across star who turns 45 years old on April 4, 2024 (2 wds.) |
| 45% | ASHTONKUTCHER | 13 | "Two and a Half Men" actor who played Michael Kelso on "That '70s Show": 2 wds. |
| 45% | BILLYCRYSTAL | 12 | 14-Across, 19-Across, and 36-Across actor and comedian who turned 75 on March 14, 2023 (2 wds.) |
| 45% | BEVERLYCLEARY | 13 | Children's author of 18-Across and 30-Across who turned 102 on April 12 (2 wds.) |
| 45% | MARKWAHLBERG | 12 | "The Lovely Bones," 14-Across, and 29-Across star who turns 50 years old tomorrow (2 wds.) |
| 44% | JEFFDANIELS | 11 | Actor who won a 2013 Emmy for playing Will McAvoy, the anchor and managing editor on 37-Across: 2 wds. |
| 44% | STEVEBURNS | 10 | 17-Across and 28-Across host/musician who turns 50 on October 9, 2023 (2 wds.) |
| 44% | CRESSWILLIAMS | 13 | "Black Lightning" actor who costars on 15-Across: 2 wds. |
| 44% | TOBIASMENZIES | 13 | 15-Across and 30-Across actor who won an Emmy for playing Prince Philip, Duke of Edinburgh, on "The Crown" (2 wds.) |
| 44% | BENFELDMAN | 10 | "Mad Men" actor who plays Jonah on 41-Across (2 wds.) |
| 44% | JACKALBERTSON | 13 | "Willy Wonka & the Chocolate Factory" actor who played "the Man" on the 1970s series "Chico and the Man": 2 wds. |