| 100% | JESSICAWALTER | 13 | "Archer" actress who played Michael Bluth's mother Lucille on "Arrested Development": 2 wds. |
| 73% | PORTIADEROSSI | 13 | "Ally McBeal" actress who played Michael Bluth's sister Lindsay on "Arrested Development": 2 wds. |
| 66% | JEFFREYTAMBOR | 13 | "Transparent" actor who played Michael Bluth's father George on "Arrested Development": 2 wds. |
| 52% | EMMYROSSUM | 10 | "Shameless" actress who plays Danny's mother on "The Crowded Room": 2 wds. |
| 51% | PORTIADEROSSI | 13 | Australian actress who plays Lindsay Bluth Fünke on "Arrested Development" (3 wds.) |
| 50% | DIANNEWIEST | 11 | "The Mule" actress who played Sam and Michael's mother Lucy in "The Lost Boys": 2 wds. |
| 50% | CONSTANCEWU | 11 | Actress who plays 36-Across's mother on "Fresh off the Boat" (2 wds.) |
| 50% | JESSICAWALTER | 13 | "Arrested Development" actress who voices Malory Archer on "Archer": 2 wds. |
| 49% | SUSANCLARK | 10 | Actress who played the adoptive mother on the 1980s sitcom "Webster": 2 wds. |
| 49% | BLYTHEDANNER | 12 | Actress who plays Will Truman's mother on "Will & Grace" (2 wds.) |
| 48% | LAURIEMETCALF | 13 | "The Conners" actress who played Sheldon's mother on "The Big Bang Theory" (2 wds.) |
| 47% | RENERUSSO | 9 | Actress who played Thor's mother Frigga: 2 wds. |
| 47% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who played Penny's mother on "The Big Bang Theory" (2 wds.) |
| 47% | TINALOUISE | 10 | Actress who played Ginger on "Gilligan's Island": 2 wds. |
| 47% | MJRODRIGUEZ | 11 | Actress who plays Blanca on FX's "Pose": 2 wds. |
| 47% | LAURENGRAHAM | 12 | "Parenthood" actress who played mother Lorelai on 14-Across: 2 wds. |
| 47% | LILIREINHART | 12 | Actress who plays Betty on the CW's "Riverdale": 2 wds. |
| 46% | LORETTASWIT | 11 | Actress who played head nurse Margaret Houlihan on "M*A*S*H": 2 wds. |
| 46% | JAMIGERTZ | 9 | "Twister" actress who played Michael's love interest Star in "The Lost Boys": 2 wds. |
| 46% | CONNIENIELSEN | 13 | "Gladiator" actress who plays Diana's mother, Queen Hippolyta: 2 wds. |
| 45% | MOLLYSHANNON | 12 | "Divorce" actress who plays the mother of the siblings on 36-Across (2 wds.) |
| 45% | SHELLEYLONG | 11 | "Cheers" actress who played Jay's ex-wife DeDe on "Modern Family": 2 wds. |
| 45% | SANDRAOH | 8 | Canadian-American actress who played Dr. Cristina Yang on "Grey's Anatomy": 2 wds. |
| 45% | RUTHWILSON | 10 | British actress who plays American Alison Lockhart on Showtime's "The Affair": 2 wds. |
| 45% | HILARYDUFF | 10 | "Lizzie McGuire" actress who plays Kelsey Peters on TV Land's "Younger": 2 wds. |
| 45% | HEIDIGARDNER | 12 | "Saturday Night Live" actress who plays Jimmy's patient Grace on "Shrinking": 2 wds. |
| 45% | CASSIDYFREEMAN | 14 | "Longmire" actress who plays Jesse's wife Amber on "The Righteous Gemstones": 2 wds. |
| 45% | NAOMIEHARRIS | 12 | Actress who played Chiron's biological mother Paula in "Moonlight": 2 wds. |
| 45% | VIOLADAVIS | 10 | "State of Play" actress who plays Michael Jordan's mother, Deloris, in the 2023 sports drama "Air" (2 wds.) |
| 45% | ANYATAYLORJOY | 13 | Actress who played child prodigy Beth Harmon on "The Queen's Gambit": 2 wds., hyph. |