| 100% | BAYOU | 5 | "Blue ___" (Roy Orbison song) |
| 92% | BLUEBAYOU | 9 | Roy Orbison song popularized by Linda Ronstadt |
| 92% | ONLY | 4 | "__ the Lonely"; Roy Orbison song |
| 91% | ANONO | 5 | "That's ___" (cautionary Roy Orbison song) |
| 85% | ITSOVER | 7 | Roy Orbison song that begins, “Your baby doesn’t love you anymore” |
| 81% | BLUEBAYOU | 9 | Roy Orbison song that was a #3 hit for 32-Across in 1977: 2 wds. |
| 81% | ITSOVER | 7 | Roy Orbison song that starts, "Your baby doesn't love you any more" (2 wds.) |
| 80% | ALLNIGHT | 8 | I Drove __; Roy Orbison's lengthy road-trip song |
| 76% | WOMAN | 5 | "Pretty ___," 1990 rom-com starring Julia Roberts, that took its title from a Roy Orbison song |
| 76% | ONLY | 4 | "___ the Lonely" (Roy Orbison song) |
| 76% | GOT | 3 | "You ___ It" (Roy Orbison song) |
| 73% | SHES | 4 | "___ a Mystery to Me" (Roy Orbison song) |
| 69% | PRETTYWOMAN | 11 | 1990 Garry Marshall film starring 17-Across and 28-Across whose title was inspired by a Roy Orbison song (2 wds.) |
| 68% | ONLY | 4 | "___ the Lonely" (Roy Orbison hit song) |
| 67% | BAYOU | 5 | "Blue ___" (hit song for both Roy Orbison and Linda Ronstadt) |
| 66% | CRYING | 6 | Emotional, tearful song by Roy Orbison |
| 66% | OHPRETTYWOMAN | 13 | Roy Orbison hit |
| 64% | DREAM | 5 | Roy Orbison's "_____ Baby" |
| 64% | ITS | 3 | Roy Orbison's "_____ Over" |
| 64% | ITS | 3 | Roy Orbison's "___ Over" |
| 64% | ITS | 3 | Roy Orbison's "— Over" |
| 64% | ONLY | 4 | "__ the Lonely"; Orbison song |
| 63% | GOT | 3 | Roy Orbison's "You ___ It" |
| 63% | ONLY | 4 | Roy Orbison's "___ the Lonely" |
| 63% | WOMAN | 5 | Roy Orbison's "Oh, Pretty ___" |
| 63% | ONLY | 4 | Roy Orbison's "__ the Lonely" |
| 63% | ALOVE | 5 | Roy Orbison’s “___ So Beautiful” |
| 60% | MOON | 4 | Blue orb of song |
| 60% | TENORS | 6 | Roy Orbison and Marvin Gaye, e.g. |
| 59% | HORNRIMMED | 10 | Like Roy Orbison's glasses |