| 100% | GEMMACHAN | 9 | "Crazy Rich Asians" actress who plays Bess of Hardwick in "Mary Queen of Scots" (2 wds.) |
| 71% | MARGOTROBBIE | 12 | "I, Tonya" actress who plays Queen Elizabeth I in "Mary Queen of Scots": 2 wds. |
| 68% | MARGOTROBBIE | 12 | "I, Tonya" actress who plays Queen Elizabeth I in "Mary Queen of Scots" (2 wds.) |
| 66% | SAOIRSERONAN | 12 | "Lady Bird" actress who plays Mary Stuart in "Mary Queen of Scots": 2 wds. |
| 64% | SAOIRSERONAN | 12 | "Lady Bird" actress who plays Mary Stuart in "Mary Queen of Scots" (2 wds.) |
| 60% | MICHELLEYEOH | 12 | "Crazy Rich Asians" actress who plays Madame Morrible in "Wicked": 2 wds. |
| 60% | MARGOTROBBIE | 12 | Actress who played 14-Across, 26-Across, and Queen Elizabeth I in "Mary Queen of Scots" (2 wds.) |
| 58% | CONSTANCEWU | 11 | "Crazy Rich Asians" actress who plays Mrs. Primm in "Lyle, Lyle, Crocodile": 2 wds. |
| 58% | SAOIRSERONAN | 12 | "Brooklyn" actress who portrayed Queen Mary in "Mary Queen of Scots": 2 wds. |
| 56% | ANGELABASSETT | 13 | Actress who plays the queen mother of Wakanda in "Black Panther": 2 wds. |
| 55% | GEMMACHAN | 9 | "Crazy Rich Asians" actress who plays Sersei in Marvel's "Eternals" (2 wds.) |
| 55% | CONSTANCEWU | 11 | "Crazy Rich Asians" actress who plays Mrs. Primm in "Lyle, Lyle, Crocodile" (2 wds.) |
| 54% | DAVIDTENNANT | 12 | "Doctor Who" actor who plays John Knox in "Mary Queen of Scots": 2 wds. |
| 53% | JULIEANDREWS | 12 | "The Sound of Music" actress who played the nanny Mary Poppins in the 1964 film: 2 wds. |
| 52% | ANYATAYLORJOY | 13 | "The Queen's Gambit" actress who plays Olga of the Birch Forest in 39-Across (2 wds.) |
| 51% | OLIVIACOLMAN | 12 | "Broadchurch" actress who plays Queen Elizabeth in season 3 of "The Crown" (2 wds.) |
| 51% | CATEBLANCHETT | 13 | Actress who played Queen Elizabeth I in the 1998 movie "Elizabeth": 2 wds. |
| 50% | EMMAROBERTS | 11 | "Scream Queens" actress who plays Mary Parker in "Madame Web" (2 wds.) |
| 49% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who plays a police officer in "Superior Donuts": 2 wds. |
| 49% | GEMMACHAN | 9 | "Crazy Rich Asians" actress who voices Raya's enemy Namaari in "Raya and the Last Dragon": 2 wds. |
| 49% | OLIVIACOLMAN | 12 | Actress who played Queen Elizabeth II on two seasons of Netflix's "The Crown": 2 wds. |
| 49% | FELICITYJONES | 13 | Actress who played Ruth Bader Ginsburg in the film "On the Basis of Sex": 2 wds. |
| 49% | FELICITYJONES | 13 | "The Theory of Everything" actress who plays Dr. Sienna Brooks in "Inferno": 2 wds. |
| 48% | EMMATHOMPSON | 12 | Oscar-winning actress who plays P.L. Travers, author of the novel "Mary Poppins," in 32-Across: 2 wds. |
| 48% | BROOKESHIELDS | 13 | Actress who played Sheila Porter in the latest season of "Law & Order: SVU": 2 wds. |
| 48% | CATEBLANCHETT | 13 | Australian actress who played Queen Elizabeth I in 1998's "Elizabeth": 2 wds. |
| 48% | MERYLSTREEP | 11 | Actress who plays Mary Wright, in the Emmy-winning drama series "Big Little Lies": 2 wds. |
| 48% | RACHELMCADAMS | 13 | Actress who plays Dr. Christine Palmer in "Doctor Strange in the Multiverse of Madness": 2 wds. |
| 48% | ZOESALDANA | 10 | "Star Trek Beyond" actress who plays Gamora in "Guardians of the Galaxy Vol. 2" (2 wds.) |
| 48% | ZOESALDANA | 10 | "Avatar" actress who played a pirate in the first "Pirates of the Caribbean" film: 2 wds. |