| 100% | MISER | 5 | "Death and the ___" (Bosch painting in the National Gallery of Art) |
| 69% | CASSATT | 7 | Her "Boating Party" is in the National Gallery of Art |
| 62% | RUBYDEE | 7 | Actress and activist who was awarded the National Medal of Arts, along with her husband, in 1995 |
| 60% | BEVERLYSILLS | 12 | Opera singer who chaired Lincoln Center and received the National Medal of Arts in 1990: 2 wds. |
| 59% | RALPHELLISON | 12 | 14-Across and 28-Across novelist who was awarded the National Medal of Arts in 1985 (2 wds.) |
| 59% | RALPHELLISON | 12 | African-American writer of 14-Across and 28-Across awarded the National Medal of Arts in 1985 (2 wds.) |
| 58% | MARILYNHORNE | 12 | Opera singer who performed at Clinton's 1993 inauguration and received the National Medal of Arts in 1992: 2 wds. |
| 54% | TATE | 4 | It began as the National Gallery of British Art |
| 54% | ODETTA | 6 | Singer awarded the National Medal of Arts in 1999 |
| 52% | JASPERJOHNS | 11 | "Three Flags" painter who received the National Medal of Arts in 1990: 2 wds. |
| 51% | RENEEFLEMING | 12 | Opera singer who sang the national anthem at the Super Bowl in 2014 and received the National Medal of Arts in 2012: 2 wds. |
| 51% | ANDREWWYETH | 11 | "Christina's World" painter who received the National Medal of Arts in 2007: 2 wds. |
| 51% | OBAMA | 5 | Subject of a Kehinde Wiley portrait in the National Portrait Gallery |
| 51% | CANDYLAND | 9 | Board game with the Peppermint Stick Forest and the Gumdrop Mountain in the National Toy Hall of Fame (2 wds.) |
| 50% | BARACKOBAMA | 11 | U.S. President who awarded Rita Moreno the National Medal of Arts in 2009 (2 wds.) |
| 50% | CHUCK | 5 | With 33-Across, "Big Self-Portrait" painter who received the National Medal of Arts in 2000 |
| 50% | LEGO | 4 | Toy brand exhibited in the gallery show "The Art of the Brick" |
| 49% | VERMEER | 7 | Artist who painted The Art of Painting in 1668 |
| 49% | MIMESIS | 7 | Representation of the real world in literature and art |
| 49% | NYAD | 4 | Long-distance swimmer Diana in the National Gay and Lesbian Sports Hall of Fame |
| 49% | JOSHUATREE | 10 | National park at the junction of the Mojave and the Colorado deserts in 52-Across (2 wds.) |
| 48% | PEI | 3 | National Gallery of Art architect |
| 48% | IMPEI | 5 | National Gallery of Art architect |
| 47% | ALICEWATERS | 11 | Chef and cookbook writer inducted into the National Women's Hall of Fame in 2017 (2 wds.) |
| 47% | TONIMORRISON | 12 | "Beloved" author who received the American Academy of Arts and Letters Gold Medal in 2019: 2 wds. |
| 47% | ELDOCTOROW | 10 | "Ragtime" author who received the American Academy of Arts and Letters Gold Medal in 2013: 3 wds. |
| 47% | MARY | 4 | & 25A Founder of the National Viewers' and Listeners' Association who died in 2001 |
| 47% | TONYKUSHNER | 11 | "Angels in America" Pulitzer winner and 2005 inductee into the American Academy of Arts and Letters: 2 wds. |
| 47% | JOHNUPDIKE | 10 | "Rabbit, Run" author who received the American Academy of Arts and Letters Gold Medal in 2007: 2 wds. |
| 46% | HEDY | 4 | Name on the Hollywood Walk of Fame ... and in the National Inventors Hall of Fame |