| 100% | BLACKHOLE | 9 | "Death by ___," nonfiction book by Neil deGrasse Tyson about astrophysics: 2 wds. |
| 39% | OURTURN | 7 | "It's ___ to Eat," book by journalist Michela Wrong about a Kenyan whistleblower: 2 wds. |
| 39% | ALLIN | 5 | Book about 32-Across that was coauthored by 1-/19-Across: 2 wds. |
| 38% | UNIVERSEIN | 10 | "The ___ a Nutshell," 2001 book about theoretical physics by Stephen Hawking: 2 wds. |
| 37% | FALLINGMAN | 10 | 2007 book by 44-Across about a survivor of the 9/11 attacks: 2 wds. |
| 37% | COSMOS | 6 | 2014 miniseries presented by Neil deGrasse Tyson |
| 36% | COSMOS | 6 | Fox science series presented by Neil deGrasse Tyson |
| 36% | SILENTSPRING | 12 | 44-Across book about the environmental harm done by pesticides that was a finalist for the 1963 National Book Award for Nonfiction (2 wds.) |
| 36% | YOU | 3 | "The good thing about science is that it's true whether or not ___ believe in it," quote by scientist Neil deGrasse Tyson |
| 35% | BIGGIRL | 7 | 2010 book by Danielle Steel about a chubby little girl and her fight with self-esteem issues: 2 wds. |
| 35% | LOSALAMOS | 9 | "___: A Whistleblower's Diary," book by Chuck Montano about foul play at a nuclear R&D site: 2 wds. |
| 35% | RUSHINGWATERS | 13 | 2016 book by Danielle Steel about six people who come together during a Hurricane in New York City: 2 wds. |
| 35% | THEHANGOVER | 11 | Movie about three friends getting drunk and wasted in Las Vegas, featuring a cameo by the boxer Mike Tyson: 2 wds. |
| 34% | COSMOS | 6 | "___: A Spacetime Odyssey," science documentary television series which is presented by Neil deGrasse Tyson |
| 33% | READA | 5 | "How to ___ Book," book by Mortimer J. Adler: 2 wds. |
| 33% | WITCHSSISTER | 12 | First book in a fantasy series about black magic by Phyllis Reynolds Naylor (2 wds.) |
| 33% | LITTLEPRINCE | 12 | "The ___," children's book written by Antoine de Saint-Exupery about a boy who leaves his tiny planet to travel the universe: 2 wds. |
| 33% | FURIOUSLYHAPPY | 14 | Memoir by 46-Across subtitled "A Funny Book About Horrible Things" (2 wds.) |
| 33% | PACKING | 7 | "___ for Mars," nonfiction book by Mary Roach about living in space |
| 33% | THEVELVETEEN | 12 | "___ Rabbit," children's book written by Margery Williams about a stuffed rabbit's desire to come to life through the owner's love: 2 wds. |
| 32% | AMA | 3 | "I ___ Child," song by Neil Young: 2 wds. |
| 32% | THEART | 6 | "___ of War," book by Sun Tzu: 2 wds. |
| 32% | NURSEBETTY | 10 | 2000 American comedy film directed by Neil LaBute, featuring Allison Janney: 2 wds. |
| 32% | MANA | 4 | "Every ___ Tiger" (1999 book by Tom Clancy): 2 wds. |
| 32% | RATHERLIE | 9 | 2025 hit by 15-Across with Playboi Carti about dishonesty: 2 wds. |
| 32% | THESANDMAN | 10 | Series of fantasy-horror comic books written by 18-Across: 2 wds. |
| 31% | HOWI | 4 | "___ Play Golf" (best-selling book by Tiger Woods): 2 wds. |
| 31% | FRECKLEJUICE | 12 | Chapter book by 38-Across about a boy who buys a potion to change his facial features (2 wds.) |
| 31% | UNIVERSE | 8 | "Finding Our Place in the ___," nonfiction book by Helene Courtois about our galaxy's home |
| 31% | SMELLYCAT | 9 | Song about a stinky feline, sung by Phoebe Buffay: 2 wds. |