| 100% | MATTERS | 7 | "Family ___," sitcom starring Jaleel White as Steve Urkel |
| 49% | FAMILYMATTERS | 13 | Chicago-based 1989-1998 sitcom starring Jaleel White: 2 wds. |
| 40% | THEUPSHAWS | 10 | Netflix sitcom starring Kim Fields as family matriarch Regina: 2 wds. |
| 39% | FAMILYMATTERS | 13 | 1989 American sitcom about the Winslow family living in Chicago starring Jaleel White: 2 wds. |
| 37% | SOAP | 4 | Tate family sitcom starring Billy Crystal |
| 37% | FATHERKNOWSBEST | 15 | Classic family sitcom starring Robert Young |
| 37% | MODERN | 6 | "___ Family," sitcom starring Nathan Lane as Pepper for which he earned three Emmy nominations |
| 35% | URKEL | 5 | Steve played by Jaleel White on “Family Matters” |
| 35% | PROUD | 5 | Disney cartoon sitcom starred this family |
| 34% | BECKER | 6 | Sitcom starring Ted Danson as a doctor |
| 34% | CHEERS | 6 | Sitcom starring Ted Danson as a bartender |
| 34% | THEBRADYBUNCH | 13 | Family sitcom starring Robert Reed and Florence Henderson that debuted in 1969 (3 wds.) |
| 34% | ALDA | 4 | Star as a sitcom surgeon |
| 34% | THEGOLDENGIRLS | 14 | Sitcom starring 29-Across as Rose Nylund (3 wds.) |
| 34% | HOTINCLEVELAND | 14 | Sitcom starring 29-Across as Elka Ostrovsky (3 wds.) |
| 33% | TEDLASSO | 8 | Sitcom starring Jason Sudeikis as a soccer coach |
| 33% | EGRET | 5 | White water bird, same family as herons |
| 32% | OFFICE | 6 | "The ___," mockumentary-style sitcom starring Steve Carell and John Krasinski |
| 32% | THEGOODPLACE | 12 | Sitcom starring Ted Danson as an immortal architect (3 wds.) |
| 32% | APBIO | 5 | Sitcom starring Glenn Howerton as a high-school science teacher |
| 32% | BETTY | 5 | ___ White, "The Golden Girls" actress who guest starred in the TV show "Family Guy" as herself |
| 32% | MODERN | 6 | "___ Family," sitcom starring Sofia Vergara |
| 32% | HOT | 3 | "___ in Cleveland," sitcom from 2010 starring Betty White as Elka Ostrovsky |
| 32% | ONOUROWN | 8 | 1990's sitcom starring a real-life rap/R & B family |
| 32% | ENGAGEMENT | 10 | "Rules of ___," sitcom starring David Spade (birthday today) as Russell Dunbar |
| 31% | FRIENDS | 7 | Popular sitcom starring Jennifer Aniston as Rachel |
| 31% | ALDA | 4 | 11-year star as a sitcom surgeon |
| 31% | RODNEY | 6 | Sitcom starring the eponymous stand-up comedian in which Sofia Vergara appeared as Carmen |
| 31% | UPALLNIGHT | 10 | NBC sitcom starring 15-/50-Across as a new mom: 3 wds. |