| 100% | TONYTODD | 8 | "Final Destination" actor who plays the title role in 16-Across: 2 wds. |
| 82% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 76% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 74% | MICHAELKEATON | 13 | "Mr. Mom" actor who played the title role in 40-Across (2 wds.) |
| 73% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 71% | TARONEGERTON | 12 | "Kingsman: The Golden Circle" actor who plays the title character in 16-Across: 2 wds. |
| 71% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 70% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role in HBO's "Perry Mason": 2 wds. |
| 69% | DWAYNEJOHNSON | 13 | "Hobbs & Shaw" actor who plays the title role in "Black Adam" (2 wds.) |
| 68% | TARONEGERTON | 12 | "Rocketman" actor who plays the title role in the 2018 film "Robin Hood" (2 wds.) |
| 68% | RUSSELLCROWE | 12 | "Gladiator" actor who plays the title role in the 2010 film "Robin Hood" (2 wds.) |
| 67% | JAREDLETO | 9 | "Blade Runner 2049" actor who plays the title role in "Morbius" (2 wds.) |
| 67% | LIAMNEESON | 10 | "Schindler's List" actor who plays the title role in "Marlowe" (2 wds.) |
| 66% | KEANUREEVES | 11 | "The Matrix Resurrections" actor who plays the title role in "John Wick: Chapter 4" (2 wds.) |
| 66% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 65% | EWANMCGREGOR | 12 | "Beauty and the Beast" actor who plays the title role in the new movie "Christopher Robin": 2 wds. |
| 65% | DEREKJACOBI | 11 | "The King's Speech" actor who plays the title role in the film "Cyrano de Bergerac" (2 wds.) |
| 65% | PATRICKSTEWART | 14 | "X-Men" actor who plays the title role on 50-Across (2 wds.) |
| 64% | ROBERTDOWNEYJR | 14 | "The Avengers" actor who played the title role in "Chaplin": 3 wds., abbr. |
| 63% | TOMELLIS | 8 | Actor who plays the titular role in the fantasy series "Lucifer": 2 wds. |
| 63% | VALKILMER | 9 | "The Doors" actor who played the title hero in 43-Across (2 wds.) |
| 63% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 62% | JULIAROBERTS | 12 | "Pretty Woman" actress who played the title role in 2000's "Erin Brockovich": 2 wds. |
| 62% | OSCARISAAC | 10 | "Star Wars" actor who plays the title superhero in 42-Across (2 wds.) |
| 62% | OLIVIAMUNN | 10 | "The Predator" actress who plays the title role in "Violet": 2 wds. |
| 62% | MIKEMYERS | 9 | "SNL" alum who played the title roles in the "Austin Powers" and "Shrek" movies: 2 wds. |
| 62% | EZRAMILLER | 10 | Actor who plays the title character in the new movie "The Flash": 2 wds. |
| 62% | MICHAELKEATON | 13 | Actor who plays Vulture, the villain in 16-Across: 2 wds. |
| 61% | RUSSELLCROWE | 12 | "Gladiator" actor who played the title boy's father in "Boy Erased": 2 wds. |
| 61% | TOMHARDY | 8 | "Inception" actor who plays the title character in "Venom": 2 wds. |