| 100% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 83% | TONYTODD | 8 | "Final Destination" actor who plays the title role in 16-Across: 2 wds. |
| 74% | TARONEGERTON | 12 | "Kingsman: The Golden Circle" actor who plays the title character in 16-Across: 2 wds. |
| 74% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 74% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 71% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 71% | MICHAELKEATON | 13 | "Mr. Mom" actor who played the title role in 40-Across (2 wds.) |
| 70% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role in HBO's "Perry Mason": 2 wds. |
| 68% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 68% | PETERDINKLAGE | 13 | "Game of Thrones" actor who plays the title character in "The Toxic Avenger": 2 wds. |
| 67% | EWANMCGREGOR | 12 | "Beauty and the Beast" actor who plays the title role in the new movie "Christopher Robin": 2 wds. |
| 67% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 67% | DWAYNEJOHNSON | 13 | "Hobbs & Shaw" actor who plays the title role in "Black Adam" (2 wds.) |
| 66% | MARKWAHLBERG | 12 | Actor from "The Italian Job", who plays the lead role of Cade Yeager in 30-Across : 2 wds. |
| 66% | BENPLATT | 8 | "The Politician" star who plays the title role in the movie adaptation of "Dear Evan Hansen": 2 wds. |
| 66% | PETEROTOOLE | 11 | "Lawrence of Arabia" actor who played the title Latin teacher in 34-Across (2 wds.) |
| 66% | JAREDLETO | 9 | "Blade Runner 2049" actor who plays the title role in "Morbius" (2 wds.) |
| 66% | LIAMNEESON | 10 | "Schindler's List" actor who plays the title role in "Marlowe" (2 wds.) |
| 65% | TARONEGERTON | 12 | "Rocketman" actor who plays the title role in the 2018 film "Robin Hood" (2 wds.) |
| 65% | RUSSELLCROWE | 12 | "Gladiator" actor who plays the title role in the 2010 film "Robin Hood" (2 wds.) |
| 65% | AUSTINBUTLER | 12 | "Once Upon a Time in Hollywood" actor who plays the title role in "Elvis" (2 wds.) |
| 65% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 64% | KEANUREEVES | 11 | "The Matrix Resurrections" actor who plays the title role in "John Wick: Chapter 4" (2 wds.) |
| 64% | JULIEANDREWS | 12 | Actress who won an Oscar for playing the title role in 39-Across: 2 wds. |
| 64% | MICHAELKEATON | 13 | Actor who plays Vulture, the villain in 16-Across: 2 wds. |
| 64% | VALKILMER | 9 | "The Doors" actor who played the title hero in 43-Across (2 wds.) |
| 64% | DEREKJACOBI | 11 | "The King's Speech" actor who plays the title role in the film "Cyrano de Bergerac" (2 wds.) |
| 63% | JULIEANDREWS | 12 | "The Sound of Music" actress who won an Oscar for playing the title role in 40-Across (2 wds.) |
| 63% | BEN | 3 | Actor Gazzara who played the title role of 15-Across in a 1975 film |
| 63% | ROD | 3 | Actor Steiger who played the title role of 15-Across in a 1959 biopic |