| 100% | MILAKUNIS | 9 | "Friends With Benefits" actress, who made a guest appearance on boyfriend Ashton Kutcher's "Two And A Half Men": 2 wds. |
| 49% | HELENHUNT | 9 | "As Good as It Gets" actress, who made a guest appearance on then-spouse Hank Azaria's "The Simpson": 2 wds. |
| 47% | SEANPENN | 8 | Two time Academy Award winning actor of "Mystic River" who appeared in a guest role on "Two and a Half Men": 2 wds. |
| 46% | BRADPITT | 8 | Actor from "Mr. & Mrs. Smith," who made a guest appearance on then-spouse Jennifer Aniston's "Friends": 2 wds. |
| 46% | CHARLIESHEEN | 12 | "Two and a Half Men" actor who was a roastee on Comedy Central Roast with Seth MacFarlane as the roast master: 2 wds. |
| 45% | ASHTONKUTCHER | 13 | Actor who replaced Charlie Sheen on "Two and a Half Men": 2 wds. |
| 44% | DENISERICHARDS | 14 | Actress who played a Bond Girl in "The World Is Not Enough" and appeared in a guest role in "Two and a Half Men": 2 wds. |
| 43% | ASHTONKUTCHER | 13 | "Two and a Half Men" actor who played Michael Kelso on "That '70s Show": 2 wds. |
| 42% | HOLLANDTAYLOR | 13 | "Two and a Half Men" actress who came out of the closet in 2015 at age 72: 2 wds. |
| 42% | LISA | 4 | ___ Kudrow, "Friends" actress who made a guest appearance on "Cheers" as Emily |
| 41% | EMMA | 4 | ___ Thompson, "Love Actually" actress who made a guest appearance on "Cheers" as a children's entertainer |
| 40% | HOLLANDTAYLOR | 13 | "Two and a Half Men" actress who was nominated for an Emmy Award for "Hollywood" (2 wds.) |
| 40% | CHAR | 4 | Actor who played a character with the same first name on "Two and a Half Men" |
| 40% | STEVEWOZNIAK | 12 | Co-founder of Apple and noted philanthropist who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 40% | ELONMUSK | 8 | CEO of SpaceX and product architect of Tesla who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 39% | PERI | 4 | ___ Gilpin, "Frasier" actress who made a guest appearance on "Cheers" as a journalist named Holly |
| 37% | CHUCKLORRE | 10 | Creator of "Two and a Half Men" and "The Big Bang Theory," who is also the co-creator of CBS's new show "Young Sheldon": 2 wds. |
| 37% | ANTONIATHOMAS | 13 | Actress who plays Shaun's friend and fellow resident Claire on 15-Across: 2 wds. |
| 37% | ASHTONKUTCHER | 13 | Actor who was part of television shows such as "Two and a Half Men" and "That '70s Show": 2 wds. |
| 36% | AMY | 3 | ___ Poehler, "Parks and Recreation" actress who made a guest appearance as the voice of Snow White in the "Shrek" franchise |
| 36% | ADAMWEST | 8 | Batman actor from the 1960s who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 36% | SEANPENN | 8 | Actor famous for "Milk" and "Mystic River" who appeared as a guest star on "Friends": 2 wds. |
| 36% | BRADPITT | 8 | Actor famous for "Fight Club" and "Troy" who appeared as a guest star on "Friends": 2 wds. |
| 35% | MEN | 3 | Ashton Kutcher's "Two and a Half ___" |
| 35% | GEORGECLOONEY | 13 | Actor who starred in and made his directorial debut with 2002's "Confessions of a Dangerous Mind": 2 wds. |
| 35% | ROSEBYRNE | 9 | "Spy" actress who's expecting a second child with her boyfriend Bobby Cannavale: 2 wds. |
| 35% | MEG | 3 | Actress Ryan who made a 2015 guest appearance on "Billy on the Street" |
| 35% | GLENDAJACKSON | 13 | English actress (1936-2023) who achieved the American Triple Crown of acting with two Oscars, three Emmys, and a Tony award (2 wds.) |
| 35% | ELIZABETHOLSEN | 14 | Actress who plays a powerful witch in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 34% | JON | 3 | Cryer who plays Alan Harper on "Two and a Half Men" |