| 100% | ADAMSANDLER | 11 | "Grown Ups" actor who played the title boy's father in "That's My Boy": 2 wds. |
| 75% | RUSSELLCROWE | 12 | "Gladiator" actor who played the title boy's father in "Boy Erased": 2 wds. |
| 74% | STEVECARELL | 11 | "The Big Short" actor who played the title boy's father in "Beautiful Boy": 2 wds. |
| 58% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 57% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role in HBO's "Perry Mason": 2 wds. |
| 55% | ZACHARYLEVI | 11 | "Chuck" actor who plays the grown-up superhero version of 38-Across in "Shazam!": 2 wds. |
| 55% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 54% | KENNETHBRANAGH | 14 | Actor who directed and played the title character in 1996's "Hamlet": 2 wds. |
| 54% | ADAMSANDLER | 11 | Actor who played the protagonist, Lenny Feder in the comedy film "Grown Ups" (released 10 years ago): 2 wds. |
| 54% | RUSSELLCROWE | 12 | "Thor: Love and Thunder" actor who plays Kraven's father Nikolai in "Kraven the Hunter": 2 wds. |
| 53% | TOMHARDY | 8 | "Inception" actor who plays the title character in "Venom": 2 wds. |
| 53% | MICHAELPENA | 11 | "Narcos: Mexico" actor who plays Dora's father in the movie mentioned in 33a: 2 wds. |
| 53% | EZRAMILLER | 10 | Actor who plays the title character in the new movie "The Flash": 2 wds. |
| 53% | TONYTODD | 8 | "Final Destination" actor who plays the title role in 16-Across: 2 wds. |
| 53% | LIAMNEESON | 10 | "Schindler's List" actor who plays the title role in "Marlowe" (2 wds.) |
| 52% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 52% | DEREKJACOBI | 11 | "The King's Speech" actor who plays the title role in the film "Cyrano de Bergerac" (2 wds.) |
| 52% | OSCARISAAC | 10 | "Inside Llewyn Davis" actor who plays Paul Atreides's father in the new movie "Dune": 2 wds. |
| 52% | ANSELELGORT | 11 | "The Fault in Our Stars" actor who plays the title character in "Baby Driver": 2 wds. |
| 52% | TARONEGERTON | 12 | "Kingsman: The Golden Circle" actor who plays the title character in 16-Across: 2 wds. |
| 52% | FERDIASHAW | 10 | Young actor who plays the title character in the 2020 movie "Artemis Fowl": 2 wds. |
| 52% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 52% | PETERDINKLAGE | 13 | "Game of Thrones" actor who plays the title character in "The Toxic Avenger": 2 wds. |
| 52% | MICHAELCIMINO | 13 | "Annabelle Comes Home" actor who plays the newly out title character in "Love, Victor": 2 wds. |
| 52% | SAMROCKWELL | 11 | Actor who plays the father in the 2015 remake of 18-Across: 2 wds. |
| 52% | JASONBIGGS | 10 | "American Pie" actor who plays the father in 18-Across: 2 wds. |
| 51% | DANIELKALUUYA | 13 | Actor who plays Slim, one of the title characters on the run in 2019's "Queen & Slim": 2 wds. |
| 51% | RENEEZELLWEGER | 14 | Actress who returns to play the title character in "Bridget Jones: Mad About the Boy": 2 wds. |
| 51% | EWANMCGREGOR | 12 | "Beauty and the Beast" actor who plays the title role in the new movie "Christopher Robin": 2 wds. |
| 51% | MICHAELPENA | 11 | "Ant-Man" actor who plays Dora's father in "Dora and the Lost City of Gold": 2 wds. |