| 100% | EMMAWOODHOUSE | 13 | "Handsome, clever, and rich" Jane Austen heroine played by 19-Across and 32-Across (2 wds.) |
| 62% | EMMAWOODHOUSE | 13 | Jane Austen title heroine described as "handsome, clever, and rich": 2 wds. |
| 47% | NURSERATCHED | 12 | Villain created by Ken Kesey played by 19-Across and 34-Across (2 wds.) |
| 44% | DWAYNEPRIDE | 11 | Special agent played by 19-Across: 2 wds. |
| 44% | EMMA | 4 | "Handsome, clever, and rich" Jane Austen character |
| 42% | STANLEYTUCCI | 12 | 19-Across and 32-Across actor who plays Dr. Abraham Erskine in "Captain America: The First Avenger" (2 wds.) |
| 41% | COSMOKRAMER | 11 | Character played by Michael Richards in "Seinfeld", who is 32-Across's neighbor and is often called a "hipster doofus": 2 wds. |
| 41% | PULITZERPRIZE | 13 | Award won by 15-, 19-, 43-, and 52-Across: 2 wds. |
| 41% | JENNIFERWORTH | 13 | Former nurse whose memoirs inspired 32-Across and the character played by Jessica Raine (2 wds.) |
| 41% | FIREFLYLANE | 11 | Bestselling novel by Kristin Hannah about two lifelong best friends that was adapted as a Netflix series starring 19-Across and 32-Across (2 wds.) |
| 40% | KRISTINHANNAH | 13 | Bestselling novelist of 19-Across and 32-Across (2 wds.) |
| 40% | FIGURESKATING | 13 | Sport featured in 19-Across and 32-Across (2 wds.) |
| 39% | CIAAGENT | 8 | Job held by the four characters from 15-, 19-, 31-, and 40-Across: 2 wds. |
| 39% | RICHARDKIMBLE | 13 | Role played by 18- and 44-Across: 2 wds. |
| 38% | LEXLUTHOR | 9 | Superman nemesis played by Gene Hackman and Jesse Eisenberg: 2 wds. |
| 38% | SILENTSPRING | 12 | Book by 19-Across that challenged the use of chemical pesticides and sparked environmentalism: 2 wds. |
| 38% | JETHROGIBBS | 11 | Special agent and former Marine played by Mark Harmon and 30-Across (2 wds.) |
| 38% | CAROLDANVERS | 12 | Alter ego of Captain Marvel played by 13-Across and 27-Across (2 wds.) |
| 38% | OCTOPUSSGARDEN | 14 | 1969 song recorded by 19-Across, and title of 41-Across's 2014 picture book: 2 wds. |
| 38% | DAMIANMCGINTY | 13 | Irish singer who played Rory Flanagan on "Glee" and was a member of 32-Across: 2 wds. |
| 38% | NEWTSCAMANDER | 13 | Character played by 15-Across in "Fantastic Beasts and Where to Find Them": 2 wds. |
| 37% | GROUNDHOGDAY | 12 | 1993 film set on February 2 starring 19-Across, 32-Across, and Bill Murray (2 wds.) |
| 37% | JOSHOCONNOR | 11 | "Emma" actor who played 32-Across in seasons 3 and 4 of "The Crown": 2 wds. |
| 37% | VITOCORLEONE | 12 | Mafia don played by both 14-Across and 28-Across in the "Godfather" franchise: 2 wds. |
| 37% | CHRISSYSNOW | 11 | Roommate of Janet Wood and Jack Tripper played by 44-Across on 15-Across (2 wds.) |
| 37% | CELESTEWRIGHT | 13 | Retired lawyer and stay-at-home mom played by Nicole Kidman in 48-Across (2 wds.) |
| 37% | THISCHRISTMAS | 13 | Holiday song by 32-Across and 2007 holiday movie starring 48-Across: 2 wds. |
| 37% | GORDONMALLOY | 12 | Helmsman and lieutenant played by Scott Grimes on 49-Across (2 wds.) |
| 37% | PETERSELLERS | 12 | Actor who played Pres. Merkin Muffley, Group Capt. Lionel Mandrake, and the title character in 32-Across: 2 wds. |
| 37% | KELLYGRAYSON | 12 | Commander and first officer played by Adrianne Palicki on 49-Across (2 wds.) |