| 100% | MANDYPATINKIN | 13 | "Homeland" actor who received cornea transplants in 1997 and 1998: 2 wds. |
| 52% | LARRYHAGMAN | 11 | "Dallas" actor who received a liver transplant in 1995: 2 wds. |
| 48% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane in "Frasier" and "Cheers", and hosted the 1998 Grammy Awards: 2 wds. |
| 44% | EDDIEMURPHY | 11 | "Coming 2 America" actor who played Doctor Dolittle in 1998 and 2001 films: 2 wds. |
| 44% | KIRKDOUGLAS | 11 | "Spartacus" actor who received the French Legion of Honor medal in 1985: 2 wds. |
| 44% | DAVIDTENNANT | 12 | Scottish actor who starred in "Doctor Who" and "Good Omens": 2 wds. |
| 44% | MACAULAYCULKIN | 14 | Child actor who starred in 19-Across and 47-Across: 2 wds. |
| 43% | MORGANFREEMAN | 13 | "Million Dollar Baby" actor who received the SAG Life Achievement Award in 2017: 2 wds. |
| 43% | WARRENBEATTY | 12 | Actor who directed, wrote, and appears in "Rules Don't Apply": 2 wds. |
| 43% | EWANMCGREGOR | 12 | Actor who appeared completely nude in "Trainspotting" and "Velvet Goldmine": 2 wds. |
| 43% | ADAMSANDLER | 11 | Actor who played Jill in "Jack and Jill": 2 wds. |
| 42% | HARRISONFORD | 12 | Actor who starred in both the "Star Wars" and "Indiana Jones" movie franchises: 2 wds. |
| 42% | SETHMACFARLANE | 14 | Actor who starred in and made his directorial debut with 2012's "Ted": 2 wds. |
| 42% | ROBBIECOLTRANE | 14 | Scottish actor who starred in "GoldenEye" and the "Harry Potter" series: 2 wds. |
| 42% | EDDIEREDMAYNE | 13 | British actor who received an Academy Award nomination for playing Lili Elbe in "The Danish Girl": 2 wds. |
| 42% | PATRICKRAFTER | 13 | Australian tennis player who won back-to-back US Opens in 1997 and 1998: 2 wds. |
| 42% | COLINHANKS | 10 | Actor who plays officer Gus Grimly in "Fargo" and whose father is Tom Hanks: 2 wds. |
| 42% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 42% | MARTINSCORSESE | 14 | "Raging Bull" director who received the AFI Life Achievement Award in 1997: 2 wds. |
| 42% | PATRICKSWAYZE | 13 | "Ghost" actor who played surfer and bank robber Bodhi in "Point Break": 2 wds. |
| 42% | EWANMCGREGOR | 12 | Scottish actor who starred in "Moulin Rouge!" and the "Star Wars" prequels: 2 wds. |
| 41% | SCOTTEASTWOOD | 13 | Actor who stars in "The Fate of the Furious", and whose father is Clint Eastwood: 2 wds. |
| 41% | FESSPARKER | 10 | Actor who starred in the title roles of TV's "Davy Crockett" and "Daniel Boone": 2 wds. |
| 41% | ANTHONYMACKIE | 13 | Actor who plays Falcon in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 41% | ROBINWILLIAMS | 13 | Actor who played Daniel Hillard, and the title character, in the 1993 film "Mrs. Doubtfire": 2 wds. |
| 41% | DANIELDAYLEWIS | 14 | "Lincoln" actor who played boxer Danny Flynn in 1997's "The Boxer": 2 wds., hyph. |
| 41% | ANTHONYMACKIE | 13 | "Avengers: Endgame" actor who plays Falcon in "The Falcon and the Winter Soldier": 2 wds. |
| 41% | HARVEYKEITEL | 12 | Actor who appeared completely nude in "Bad Lieutenant" and "The Piano": 2 wds. |
| 41% | JADENSMITH | 10 | Actor who starred in "The Karate Kid" alongside Jackie Chan, and whose father is Will Smith: 2 wds. |
| 41% | BRADLEYCOOPER | 13 | Actor who starred in and made his directorial debut with 2018's "A Star Is Born": 2 wds. |