| 100% | INHIS | 5 | "It's ___ Kiss" (subtitle of "The Shoop Shoop Song") |
| 69% | HIS | 3 | "The Shoop Shoop Song (It's in ___ Kiss)" |
| 68% | HIS | 3 | "The Shoop Shoop Song (It's in ___ Kiss)" (Cher hit) |
| 65% | EVERETT | 7 | Betty who sang "The Shoop Shoop Song (It's in His Kiss)" |
| 63% | ASWE | 4 | "It's the End of the World ___ Know It" (R.E.M. song) |
| 63% | KNOW | 4 | "It's the End of the World as We ___ It" (R.E.M. song) |
| 60% | ASWE | 4 | "It's the End of the World ___ Know It (And I Feel Fine)" (R.E.M. song) |
| 59% | AHA | 3 | "I remember the name of the song now. It's 'Take On Me'!" |
| 59% | ASWE | 4 | "It's the End of the World ___ Know It (And I Feel Fine)" (R.E.M. song): 2 wds. |
| 58% | JESS | 4 | "Who's that girl? It's ___!" (end of the theme song to "New Girl") |
| 58% | OOHLALA | 7 | It may be said after kissing the tips of one's fingers |
| 58% | SEED | 4 | Subject of the "Lorax" song "Let It Grow" |
| 58% | MTOSSA | 6 | It's S. of the Vale of Tempe |
| 57% | SEALED | 6 | "__ with a Kiss"; song of the '60s |
| 57% | SAOTOME | 7 | It's just north of the equator |
| 57% | ASSAM | 5 | It's just south of the Himalayas |
| 57% | NORM | 4 | It's not out of the ordinary |
| 57% | NOSE | 4 | It's in front of the cockpit |
| 57% | OPENSECRET | 10 | It's already out of the bag |
| 57% | ADRENALINE | 10 | It's often part of the rush |
| 57% | SCENE | 5 | It's just part of the act |
| 57% | SCENE | 5 | It's all part of the act |
| 57% | USE | 3 | "It's in the Way That You ___ It" (Clapton song in "The Color of Money") |
| 56% | USE | 3 | "It's in the Way That You ___ It" (Eric Clapton song in "The Color of Money") |
| 55% | ITSIN | 5 | "The Shoop Shoop Song (___ His Kiss)" (2 wds.) |
| 55% | MOST | 4 | "It's the ___ Wonderful Time of the Year" (Christmas song) |
| 55% | OSOLEMIO | 8 | Basis of the song "It's Now or Never" |
| 55% | HOW | 3 | It's not one of the five W's |
| 55% | ESTREET | 7 | It's directly south of the White House lawn |
| 55% | OED | 3 | It's 2021 word of the year was "vax" |