| 100% | ERINMORIARTY | 12 | "Jessica Jones" actress who plays Starlight/Annie January on "The Boys" (2 wds.) |
| 66% | KRYSTENRITTER | 13 | Actress who plays the Marvel Comics hero Jessica Jones in "Jessica Jones" and "The Defenders" on Netflix (2 wds.) |
| 65% | CONSTANCEWU | 11 | Actress who plays Jessica, the mom on "Fresh Off the Boat": 2 wds. |
| 62% | KRYSTENRITTER | 13 | Actress who plays Jessica Jones in "The Defenders": 2 wds. |
| 59% | KRYSTENRITTER | 13 | "Jessica Jones" actress who plays Lucy in the "Echoes" spin-off of 18-Across: 2 wds. |
| 58% | AMBERRILEY | 10 | "The Wiz Live!" actress who played Mercedes Jones on "Glee": 2 wds. |
| 58% | JUNOTEMPLE | 10 | Actress who played Keeley Jones on "Ted Lasso": 2 wds. |
| 58% | EMILYMORTIMER | 13 | Actress who plays MacKenzie McHale, the executive producer on 37-Across: 2 wds. |
| 58% | LILIREINHART | 12 | Actress who plays Betty Cooper on the CW teen drama "Riverdale": 2 wds. |
| 58% | SUSANCLARK | 10 | Actress who played the adoptive mother on the 1980s sitcom "Webster": 2 wds. |
| 57% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 57% | ALLISONJANNEY | 13 | Actress who plays Bonnie, the title mom on "Mom": 2 wds. |
| 57% | LILIREINHART | 12 | Actress who plays Betty on the CW's "Riverdale": 2 wds. |
| 57% | KENNEDYMCMANN | 13 | Actress who plays the title role on "Nancy Drew": 2 wds. |
| 57% | POLLYHOLLIDAY | 13 | Actress who played waitress Flo on the sitcom "Alice": 2 wds. |
| 57% | COURTENEYCOX | 12 | Actress who played the chef Monica Geller on "Friends": 2 wds. |
| 57% | LINDALAVIN | 10 | Actress who played the title character on the sitcom "Alice": 2 wds. |
| 57% | EARTHAKITT | 10 | Actress who played Catwoman on the 1960s TV series "Batman": 2 wds. |
| 57% | TALITHABATEMAN | 14 | "Annabelle: Creation" actress who plays the astronaut's daughter on "Away": 2 wds. |
| 57% | ODETTEANNABLE | 13 | "Supergirl" actress who plays Geri Broussard on The CW's "Walker": 2 wds. |
| 57% | JENNAORTEGA | 11 | "Scream" actress who plays Wednesday Addams on the Netflix series "Wednesday": 2 wds. |
| 57% | ELLAPURNELL | 11 | "Yellowjackets" actress who plays Lucy MacLean on the Amazon series "Fallout": 2 wds. |
| 56% | RACHELMCADAMS | 13 | Actress who plays Annie in the 2018 action comedy film "Game Night": 2 wds. |
| 56% | BARBARABAIN | 11 | Actress who played Cinnamon Carter on the 1966-1973 series "Mission: Impossible": 2 wds. |
| 56% | JULIALOUIS | 10 | ___-Dreyfus, actress who played Elaine Benes on the show "Seinfeld": 2 wds. |
| 56% | RENEEZELLWEGER | 14 | Actress who returns to play the title character in "Bridget Jones: Mad About the Boy": 2 wds. |
| 56% | LUCYLIU | 7 | Actress who played Joan (based on 47-Across) on the CBS series "Elementary": 2 wds. |
| 56% | CHERYLHINES | 11 | Actress who plays the main character's ex-wife on "Curb Your Enthusiasm": 2 wds. |
| 56% | EDIEFALCO | 9 | "The Sopranos" actress who played the title character on "Nurse Jackie": 2 wds. |
| 56% | JEANSTAPLETON | 13 | Actress who played mom Edith Bunker on "All in the Family": 2 wds. |