| 100% | RUTHELIZABETH | 13 | "Jezebel" actress ___ "Bette" Davis who became the first female recipient of the AFI Life Achievement Award: 2 wds. |
| 47% | CANDICEBERGEN | 13 | Actress who was the first female host of "Saturday Night Live": 2 wds. |
| 45% | JAMESCAGNEY | 11 | "White Heat" star who was the second actor to receive the AFI Life Achievement Award after John Ford: 2 wds. |
| 44% | LILLIANGISH | 11 | "The Birth of a Nation" star who is the only silent era actor to win the AFI Life Achievement Award: 2 wds. |
| 43% | DIANEKEATON | 11 | Comedic actress who was given an AFI Life Achievement Award on June 8: 2 wds. |
| 41% | ANGELINAJOLIE | 13 | "Changeling" and "Tomb Raider" actress who is the daughter of famed Academy Award recipient Jon Voight: 2 wds. |
| 41% | TAYLORSWIFT | 11 | Multiple Grammy-winning singer-songwriter who is the first-ever recipient of Billboard's Woman of the Decade Award: 2 wds. |
| 41% | MIKENICHOLS | 11 | "The Graduate" director who received the AFI Life Achievement Award in 2010: 2 wds. |
| 40% | CAROLBURNETT | 12 | "The Four Seasons" actress who received the SAG Life Achievement Award in 2015: 2 wds. |
| 40% | GEORGELUCAS | 11 | "Star Wars" director who received the AFI Life Achievement Award in 2005: 2 wds. |
| 40% | MARTINSCORSESE | 14 | "Raging Bull" director who received the AFI Life Achievement Award in 1997: 2 wds. |
| 40% | MARIECURIE | 10 | Scientist who was the first female professor at the University of Paris: 2 wds. |
| 40% | NANCYPELOSI | 11 | Democratic congresswoman from California who was the first female Speaker of the House: 2 wds. |
| 40% | CANDICEBERGEN | 13 | "Murphy Brown" star who was the first female host of "Saturday Night Live": 2 wds. |
| 40% | JUDYGARLAND | 11 | First female recipient of the Cecil B. DeMille lifetime achievement award in film |
| 40% | VANDYKE | 7 | Dick ___, recipient of the SAG lifetime achievement award in 2013: 2 wds. |
| 38% | BETTYFORD | 9 | First Lady who wrote the 1978 memoir "The Times of My Life": 2 wds. |
| 38% | ANNPRESTON | 10 | American physician and activist who was the first female dean of a medical school in the world: 2 wds. |
| 38% | NAOMICAMPBELL | 13 | "American Horror Story: Hotel" actress who was the first black model on the cover of French Vogue : 2 wds. |
| 38% | ANNAFARIS | 9 | Actress who played Christy Plunkett on the first seven seasons of the CBS sitcom "Mom": 2 wds. |
| 37% | ALANALDA | 8 | "M*A*S*H" star who was the winner of the 2019 SAG Life Achievement Award (2 wds.) |
| 37% | NICOLEKIDMAN | 12 | "The Hours" Oscar winner who was honored with an AFI Life Achievement Award in 2024 (2 wds.) |
| 37% | SOLANGEKNOWLES | 14 | 12-Across and 28-Across singer who was the first recipient of the "Billboard" Women in Music Impact Award (2 wds.) |
| 37% | DEBBIEHARRY | 11 | Lead singer of Blondie who received the first Billboard Women in Music Icon Award, in 2008: 2 wds. |
| 37% | JENNADEWAN | 10 | "Step Up" actress who was the first host of "World of Dance": 2 wds. |
| 36% | JILLARRINGTON | 13 | Female sportscaster who is the aunt of actress Dakota Fanning: 2 wds. |
| 36% | RAMIMALEK | 9 | Actor who became the first one of Egyptian heritage to win an Oscar for Best Actor in 2019: 2 wds. |
| 36% | SMOKEYROBINSON | 14 | "I Second That Emotion" singer who won one of the first Grammy Legend Awards, in 1990: 2 wds. |
| 36% | WILLIENELSON | 12 | "Always on My Mind" singer who won one of the first Grammy Legend Awards, in 1990: 2 wds. |
| 36% | PATSYCLINE | 10 | American singer (birthday today) who was the first female solo artist inducted to the Country Music Hall of Fame: 2 wds. |