| 100% | FALLENKINGDOM | 13 | "Jurassic World: ___," Universal Pictures' 2018 sci-fi film that made over $100 million over two consecutive non-holiday weekends: 2 wds. |
| 31% | PACIFICRIM | 10 | 2013 Guillermo del Toro sci-fi/monster movie that earned over $400 million worldwide: 2 wds. |
| 31% | BLACKPANTHER | 12 | Marvel's 2018 superhero film that became the first film since "Avatar" to top the box office for five consecutive weekends: 2 wds. |
| 30% | WEARE | 5 | "___ the World" (1985 song that raised over $60 million for charity): 2 wds. |
| 29% | FORRESTGUMP | 11 | Non-Disney film that grossed around $330 million in 1994 (2 wds.) |
| 27% | AFTEREARTH | 10 | 2013 sci-fi film that features Will Smith and his real-life son Jaden: 2 wds. |
| 27% | STARWARS | 8 | 1977 George Lucas film that launched a sci-fi franchise: 2 wds. |
| 26% | THESANTACLAUSE | 14 | Non-animated Disney film that grossed around $145 million in 1994 (3 wds.) |
| 25% | INSIDEOUT | 9 | "Emotional" movie from Pixar that grossed over $850 million worldwide: 2 wds. |
| 25% | MISSIONTO | 9 | "___ Mars," American sci-fi film from 2000 about a manned exploration mission to Mars that goes wrong: 2 wds. |
| 25% | CASHCOW | 7 | Business that makes money hand over fist: 2 wds. |
| 25% | PARK | 4 | "Jurassic ___," sci-fi film franchise about dinosaurs that took over cereal boxes in the '90s |
| 25% | THESHAPEOF | 10 | With 55-Across, 2017 Guillermo del Toro sci-fi/fantasy film that won Best Picture and three other Oscars: 3 wds. |
| 25% | IROBOT | 6 | 1950 sci-fi fixup novel by Isaac Asimov that shares its title with a 2004 film starring Will Smith: 2 wds. |
| 25% | ALIENROMULUS | 12 | New sci-fi horror movie that's the seventh film in a franchise that began in 1979: 2 wds. |
| 25% | MARYPOPPINS | 11 | With 41-Across, 2018 Emily Blunt film that's a sequel to a 1964 Julie Andrews film: 2 wds. |
| 24% | GODSPLAN | 8 | 2018 Drake track that debuted at #1 on the Billboard Hot 100: 2 wds. |
| 24% | STARWARS | 8 | George Lucas sci-fi film series that debuted in 1977 (2 wds.) |
| 24% | HOUSTONASTROS | 13 | Minute Maid Park team that won the 2022 World Series four games to two over the Philadelphia Phillies (2 wds.) |
| 24% | AVATAR | 6 | Sci fi film that went really big |
| 24% | STARWARS | 8 | George Lucas sci-fi film series that debuted on May 25, 1977 (2 wds.) |
| 24% | THEGREATEST | 11 | With 42-Across, 1952 circus film that won the Best Picture Oscar: 2 wds. |
| 24% | READYPLAYERONE | 14 | 2018 sci-fi film in which Olivia Cooke portrayed Art3mis: 3 wds. |
| 23% | GODSPLAN | 8 | Drake song that was #1 on Billboard's 2018 Year-End Hot 100: 2 wds. |
| 23% | DAVINCI | 7 | "The ___ Code," 2003 novel by Dan Brown that was made into a film: 2 wds. |
| 23% | JURASSICWORLD | 13 | 2015 sci-fi adventure film about a theme park of cloned dinosaurs, that is the fifth highest-grossing film of all time: 2 wds. |
| 23% | THEFATEOFTHE | 12 | F. Gary Gray's 2017 action film "___ Furious," made with a budget of $250 million and which grossed over $1.2 billion worldwide: 4 wds. |
| 23% | GREENBOOK | 9 | 2018 drama starring Mahershala Ali that's one of six PG-13 films to win a Best Picture Oscar in the 21st century (2 wds.) |
| 23% | ALIEN | 5 | 1979 sci-fi film that features Howard Hanson's "Symphony No. 2" |
| 23% | DOCTORWHO | 9 | BBC sci-fi series that debuted in 1963: 2 wds. |