| 100% | LITTLERICHARD | 13 | "Long Tall Sally" singer played by Brandon Mychal Smith in "Get On Up": 2 wds. |
| 52% | MICKJAGGER | 10 | Rolling Stones singer played by Nick Eversman in "Get On Up": 2 wds. |
| 40% | JAMES | 5 | With 50-Across, soul singer played by Chadwick Boseman in the 2014 biopic "Get On Up" |
| 40% | JAMESBROWN | 10 | Subject of the new biopic "Get On Up," played by Chadwick Boseman: 2 wds. |
| 39% | TINATURNER | 10 | Singer played by Angela Bassett in the 1993 musical biopic "What's Love Got to Do with It" (2 wds.) |
| 39% | RACHELBERRY | 11 | Vegetarian singer played by Lea Michele on "Glee": 2 wds. |
| 37% | LORETTALYNN | 11 | Country singer played by 44-Across in the 1980 biopic "Coal Miner's Daughter": 2 wds. |
| 36% | PRINCESSDIANA | 13 | British royal played by Emma Corrin on "The Crown" in 2020: 2 wds. |
| 36% | QUEENELIZABETH | 14 | British royal played by Olivia Colman on "The Crown" in 2020: 2 wds. |
| 36% | NINASIMONE | 10 | Singer played by Zoe Saldaña in a 2016 musical biopic (2 wds.) |
| 35% | JIMMORRISON | 11 | Singer played by Val Kilmer in the music biopic "The Doors" (2 wds.) |
| 35% | ARETHAFRANKLIN | 14 | Singer played by Jennifer Hudson in the 2021 musical biopic "Respect" (2 wds.) |
| 35% | PRINCECHARLES | 13 | British royal played by Josh O'Connor on Netflix's "The Crown" in 2020: 2 wds. |
| 34% | BRIANWILSON | 11 | Singer played by Paul Dano and John Cusack in the music biopic "Love & Mercy" (2 wds.) |
| 34% | WHITNEYHOUSTON | 14 | Singer played by Naomi Ackie in the 2022 musical biopic "I Wanna Dance with Somebody" (2 wds.) |
| 34% | THEDOCTOR | 9 | Time Lord whose 11th incarnation was played by 15-Across on a long-running BBC sci-fi series: 2 wds. |
| 33% | RITCHIEVALENS | 13 | Singer played by Lou Diamond Phillips in the music biopic "La Bamba" (2 wds.) |
| 33% | RAFESADLER | 10 | Character played by actor Thomas Brodie-Sangster in the British television serial "Wolf Hall" based on Hilary Mantel novels: 2 wds. |
| 32% | FRANKIEDRAKE | 12 | 1920s private detective in Toronto played by Lauren Lee Smith on a 2017-2021 Canadian TV series (2 wds.) |
| 31% | JEREMYCAMP | 10 | Singer/songwriter played by K.J. Apa in 31-Across (2 wds.) |
| 31% | CHRISDAUGHTRY | 13 | "Home" singer playing Judas in 42-Across: 2 wds. |
| 31% | ADAMMAYFAIR | 11 | Gynecologist played by Nathan Fillion on "Desperate Housewives": 2 wds. |
| 31% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 31% | JOHNSTEED | 9 | Spy played by Patrick Macnee on "The Avengers": 2 wds. |
| 31% | JIMPHELPS | 9 | Spy played by Peter Graves on "Mission: Impossible": 2 wds. |
| 31% | JENNIFERMELFI | 13 | Psychiatrist played by Lorraine Bracco on "The Sopranos": 2 wds. |
| 31% | ARIANAGRANDE | 12 | Pop singer playing Penny Pingleton in 30-Across: 2 wds. |
| 31% | STEVEURKEL | 10 | Geeky character played by Jaleel White on "Family Matters": 2 wds. |
| 31% | DRWATSON | 8 | Holmes' assistant, played by 29-Across on 47-Across: 2 wds. |
| 31% | AVONBARKSDALE | 13 | Drug dealer played by Wood Harris on "The Wire": 2 wds. |