| 100% | CHRISPERFETTI | 13 | "Looking" actor who plays a history teacher and ally of 15-Across: 2 wds. |
| 60% | LISAANNWALTER | 13 | "Bruce Almighty" actress who plays a teacher and ally of 15-Across: 3 wds. |
| 58% | ZACEFRON | 8 | Actor who plays a protégé of 15-Across in "The Greatest Showman": 2 wds. |
| 56% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 50% | CHRISEVANS | 10 | "Avengers: Endgame" actor who plays a cult leader in 15-Across: 2 wds. |
| 49% | CHARLIEDAY | 10 | "It's Always Sunny in Philadelphia" actor who plays a detective in 15-Across: 2 wds. |
| 49% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 47% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 47% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 46% | PAULBETTANY | 11 | Actor who plays a powerful android in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 46% | BENEDICTWONG | 12 | "Doctor Strange" actor who plays a master of the mystic arts in 24-Across (2 wds.) |
| 46% | LESLIENIELSEN | 13 | "Airplane!" actor who played a vampire in the comedy "Dracula: Dead and Loving It": 2 wds. |
| 46% | BRUCEWILLIS | 11 | "Die Hard" actor who plays a man with superhuman strength in "Unbreakable" and 62-Across (2 wds.) |
| 45% | JEFFDANIELS | 11 | Actor who won a 2013 Emmy for playing Will McAvoy, the anchor and managing editor on 37-Across: 2 wds. |
| 45% | JEREMYPIVEN | 11 | "Entourage" actor who plays a tech innovator in the new CBS drama "Wisdom of the Crowd": 2 wds. |
| 45% | ALANRICKMAN | 11 | Actor who played Professor Snape and was a misunderstood character in "Harry Potter" series: 2 wds. |
| 45% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 45% | BENMENDELSOHN | 13 | Actor who plays the character of Talos, a shape shifting Skrull leader in "Captain Marvel": 2 wds. |
| 45% | JUDDNELSON | 10 | Actor who played a high school delinquent in "The Breakfast Club" and a yuppie politician in "St. Elmo's Fire": 2 wds. |
| 45% | EMILIOESTEVEZ | 13 | Actor who played a high school jock in "The Breakfast Club" and a law student in "St. Elmo's Fire": 2 wds. |
| 44% | ALECBALDWIN | 11 | Actor who plays Alan Hunley in the fifth and sixth installment of the "Mission: Impossible" series: 2 wds. |
| 44% | MICHAELCERA | 11 | "Barbie" actor who plays the head of a viral marketing firm in 26-Across (2 wds.) |
| 44% | DAVIDMCCALLUM | 13 | Actor who currently plays 15-Across and once played 50-Across: 2 wds. |
| 44% | JAMESBROLIN | 11 | Actor who played a physician on 28-Across: 2 wds. |
| 44% | DAVIDTENNANT | 12 | Scottish actor who played Barty Crouch, Jr. in "Harry Potter and the Goblet of Fire": 2 wds. |
| 44% | TOBIASMENZIES | 13 | 15-Across and 30-Across actor who won an Emmy for playing Prince Philip, Duke of Edinburgh, on "The Crown" (2 wds.) |
| 44% | ERICBANA | 8 | Actor who played 32-Across in a 2003 film: 2 wds. |
| 44% | EDWARDNORTON | 12 | Actor who played 32-Across in a 2008 film: 2 wds. |
| 44% | PETERSTORMARE | 13 | Actor who plays John Abruzzi and is a prominent figure at Fox River State Penitentiary in "Prison Break": 2 wds. |
| 44% | MICHAELPENA | 11 | "Ant-Man" actor who plays Dora's father in "Dora and the Lost City of Gold": 2 wds. |