| 100% | MRSMAISEL | 9 | "Marvelous" stand-up comic and title character of an Emmy-winning Amazon series: 2 wds. |
| 37% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 35% | CALVIN | 6 | Comics title character who says "Getting an inch of snow is like winning 10 cents in the lottery" |
| 35% | LOUISCK | 7 | Stand-up comedian who created and stars in an award-winning FX series: 3 wds. |
| 34% | MADMEN | 6 | Series for which Jon Hamm won an Emmy: 2 wds. |
| 34% | AMYDORRIT | 9 | Title character of an 1857 novel by Charles Dickens born and raised in the Marshalsea debtors' prison |
| 34% | JOHNMULANEY | 11 | Stand-up comic and former "SNL" writer who first returned to host in 2018: 2 wds. |
| 34% | SAMURAIJACK | 11 | Sword-wielding title character in a 2001-2004 and 2017 Cartoon Network series: 2 wds. |
| 33% | TVSTAR | 6 | Type of performer who could win an Emmy: 2 wds. |
| 33% | DRNO | 4 | Title villain of an early James Bond film: 2 wds. |
| 33% | SONICTHE | 8 | With 42-Across, speedy blue title character of a 2020 film: 2 wds. |
| 32% | CARLSAGAN | 9 | Host of an Emmy-winning PBS series |
| 32% | LIANEMORIARTY | 13 | Author of the novel "Big Little Lies" which was adapted into an Emmy-winning TV series: 2 wds. |
| 32% | FRANFINE | 8 | Title character of 15-Across, whose first name is shared by actress Drescher who plays her: 2 wds. |
| 32% | ELTONJOHN | 9 | "Crocodile Rock" singer who is an Emmy away from completing the EGOT (winning an Emmy, Grammy, Oscar, and Tony): 2 wds. |
| 32% | MARTINLAWRENCE | 14 | Stand-up comedian and star of a 1990s Fox sitcom, whose title was his first name: 2 wds. |
| 32% | ALF | 3 | Title character of an '80s sitcom |
| 31% | STANMUSIAL | 10 | Cardinal Hall of Famer who won MVP awards as an outfielder (1943, 1948) and a first baseman (1946): 2 wds. |
| 31% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" star who played the title character of 28-Across in a 2015 movie: 2 wds. |
| 31% | BROSNAHAN | 9 | Actress Rachel who plays 48-Across on an Emmy-winning Amazon series |
| 31% | CHARLIESANGELS | 14 | Classic ABC crime drama series whose title character employs private investigators Jill, Kelly, and Sabrina: 2 wds. |
| 31% | BEATRIXPOTTER | 13 | Author/illustrator who created the title character of 18-Across: 2 wds. |
| 30% | BILLHADER | 9 | "Trainwreck" actor nominated for an Emmy in 2018 for directing an episode of "Barry": 2 wds. |
| 30% | JASONBATEMAN | 12 | "Arrested Development" actor nominated for an Emmy in 2018 for directing an episode of "Ozark": 2 wds. |
| 30% | OCTOPUSSGARDEN | 14 | 1969 song recorded by 19-Across, and title of 41-Across's 2014 picture book: 2 wds. |
| 30% | TEMPLEGRANDIN | 13 | 2010 biographical drama film based on the life of an American scientist and autism advocate: 2 wds. |
| 30% | GATSBY | 6 | Jay ___, title character of an F. Scott Fitzgerald book |
| 30% | LORETTADEVINE | 13 | Star of 15-Across who won an Emmy for a guest performance in "Grey's Anatomy": 2 wds. |
| 29% | RICHARDCASTLE | 13 | Writer who was the title character in a 2009-2016 crime series: 2 wds. |
| 29% | WILLSMITH | 9 | Lead actor and main character of "The Fresh Prince of Bel-Air": 2 wds. |