| 100% | TRES | 4 | "Maya y los ___" (animated Netflix series featuring the voices of Zoe Saldaña and Rita Moreno) |
| 50% | FAMILYGUY | 9 | Animated TV series featuring the voices of Seth MacFarlane and 43-Across (2 wds.) |
| 50% | FAMILYGUY | 9 | Animated TV series featuring the voices of Seth MacFarlane and 42-Across (2 wds.) |
| 49% | CARMENSANDIEGO | 14 | Netflix animated adventure series featuring the voice of 49-Across as the title character (2 wds.) |
| 45% | KINGOFTHE | 9 | US animated television series featuring the voice talent of Mike Judge and Kathy Najimy that ran from 1997-2010 |
| 44% | FAMILYGUY | 9 | Seth MacFarlane animated series featuring the voices of 15-Across, 26-Across, and 34-Across that debuted in 1999 (2 wds.) |
| 43% | IAMNOTAN | 8 | & 6D 2004 BBC TV animated comedy series featuring the voice talent of Steve Coogan and Amelia Bullmore |
| 41% | ANTZ | 4 | Animated film featuring the voices of Gene Hackman and Sylvester Stallone |
| 40% | ARCANE | 6 | "___: League of Legends" (Netflix animated series featuring the voice of Hailee Steinfeld) |
| 38% | WRECKITRALPH | 12 | 2012 animated film featuring the voices of John C. Reilly and Sarah Silverman: 2 wds. |
| 37% | MODOK | 5 | 2021 animated series based on a Marvel Comics character and featuring the voices of Aimee Garcia and Ben Schwartz |
| 37% | ARCHER | 6 | FX animated comedy series featuring H. Jon Benjamin as the voice of a narcissistic spy |
| 37% | EPIC | 4 | 2013 animated film featuring the voice talent of Colin Farrell and Josh Hutcherson |
| 37% | CARS | 4 | 2006 animated film featuring the voice talent of Owen Wilson and Paul Newman |
| 37% | RIO | 3 | 2011 animated film featuring the voice talent of Jesse Eisenberg and Anne Hathaway |
| 37% | EPIC | 4 | 2013 animated film featuring the voice talents of Colin Farrell and Josh Hutcherson |
| 37% | MEGAMIND | 8 | 2010 animated film featuring the voice talent of Will Ferrell and Brad Pitt |
| 37% | ROBOTS | 6 | 2005 animated film featuring the voice talent of Mel Brooks and Jim Broadbent |
| 37% | BOLT | 4 | 2008 animated film featuring the voice talent of John Travolta and Miley Cyrus |
| 37% | SHREK | 5 | 2001 animated film featuring the voice talent of Mike Myers and Eddie Murphy |
| 37% | SHREK | 5 | 2001 animated film featuring the voice talents of Mike Myers and Eddie Murphy |
| 36% | ICEAGE | 6 | Animated film franchise featuring the voice of Ray Romano (2 wds.) |
| 35% | SPACE | 5 | & 17A 2008 animated film featuring the voice talent of Andy Samberg and Cheryl Hines |
| 35% | CHICKEN | 7 | & 11D 2000 animated film featuring the voice talent of Mel Gibson and Julia Sawalha |
| 35% | GOOSE | 5 | "Duck Duck ___" (2018 animated film featuring the voices of Jim Gaffigan and Zendaya) |
| 34% | THEWILDROBOT | 12 | 2024 animated film featuring the voices of Pedro Pascal, 14-Across, and 31-Across about an automaton who befriends animals on a remote island (3 wds.) |