| 100% | HILARYSWANK | 11 | "Million Dollar Baby" actress who plays a journalist whose son was murdered in 31-Across (2 wds.) |
| 48% | HILARYSWANK | 11 | "Million Dollar baby" actress who plays a hairdresser who rallies her town during a blizzard to help a critically ill girl in "Ordinary Angels" (2 wds.) |
| 46% | WHITNEYHOUSTON | 14 | Singer and actress who played Rachel Marron in 18a and whose cover of "I Will Always Love You" became a best-selling single: 2 wds. |
| 46% | GRACEKELLY | 10 | Actress who played a socialite in Hitchcock's "Dial M for Murder": 2 wds. |
| 46% | KIRSTENDUNST | 12 | "The Power of the Dog" actress who plays a journalist in the new movie "Civil War": 2 wds. |
| 45% | OLIVIACOOKE | 11 | "Ready Player One" actress who plays the pregnant girlfriend of a murdered man in 31-Across (2 wds.) |
| 45% | HELENMIRREN | 11 | "The Queen" actress who plays a retired intelligence agent in "The Thursday Murder Club": 2 wds. |
| 44% | HILARYSWANK | 11 | "Million Dollar Baby" actress who plays high-school teacher Erin Gruwell in "Freedom Writers" (2 wds.) |
| 44% | HILARYSWANK | 11 | Oscar-winning actress who plays boxer Maggie Fitzgerald in "Million Dollar Baby" (2 wds.) |
| 44% | KARYNPARSONS | 12 | Actress who played the snobbish cousin of 17-Across in "The Fresh Prince of Bel-Air," which is rumored to be getting a reunion: 2 wds. |
| 43% | PHOEBECATES | 11 | Actress who plays a bank employee whose boyfriend gets a monstrous Christmas gift in "Gremlins" (2 wds.) |
| 43% | CAREYMULLIGAN | 13 | "The Great Gatsby" actress who plays a feminist in 42-Across: 2 wds. |
| 43% | MERYLSTREEP | 11 | "Into the Woods" actress who plays a feminist in 42-Across: 2 wds. |
| 43% | SANDRABULLOCK | 13 | "The Blind Side" actress who played a crossword constructor in 33-Across: 2 wds. |
| 43% | HILARYSWANK | 11 | "Million Dollar Baby" actress who plays Eileen on 44-Across (2 wds.) |
| 43% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 43% | DENISERICHARDS | 14 | Actress who played a Bond Girl in "The World Is Not Enough" and appeared in a guest role in "Two and a Half Men": 2 wds. |
| 43% | INGRIDBERGMAN | 13 | "Casablanca" actress who played a Swedish missionary in "Murder on the Orient Express": 2 wds. |
| 43% | SASHEERZAMATA | 13 | 30-Down actress who plays a journalist on "Woke": 2 wds. |
| 42% | CRISTINMILIOTI | 14 | Actress who plays a wedding guest who's stuck in a time loop in 44-Across: 2 wds. |
| 42% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who plays a police officer in "Superior Donuts": 2 wds. |
| 42% | ANYATAYLORJOY | 13 | "Glass" actress who played 19-Across in a 2020 film: 2 wds., hyph. |
| 42% | MARGOTROBBIE | 12 | Actress who plays a fictional associate producer in "Bombshell": 2 wds. |
| 42% | MERYLSTREEP | 11 | "The Devil Wears Prada" actress who plays a struggling actress on "Only Murders in the Building" (2 wds.) |
| 42% | LEAMICHELE | 10 | Actress who plays 17-Across' girlfriend and was 29-Across' girlfriend in real life: 2 wds. |
| 41% | TESSATHOMPSON | 13 | "Thor: Ragnarok" actress who plays a surveyor in "Annihilation": 2 wds. |
| 41% | NATALIEPORTMAN | 14 | "Black Swan" actress who plays a biologist in "Annihilation": 2 wds. |
| 41% | MIAWASIKOWSKA | 13 | Actress who played the daughter of 14- and 32-Across in "The Kids Are All Right": 2 wds. |
| 41% | AUBREYPLAZA | 11 | Actress who plays a profane 14th-century nun in "The Little Hours": 2 wds. |
| 41% | BLAKELIVELY | 11 | Actress who wore contact lenses she couldn't see through to play a blind woman in "All I See Is You": 2 wds. |