| 100% | OLYMPIADUKAKIS | 14 | "Moonstruck" actress who played Mollie's mother Rosie in "Look Who's Talking": 2 wds. |
| 74% | KIRSTIEALLEY | 12 | "Cheers" actress who played Mollie Jensen in 1989's "Look Who's Talking": 2 wds. |
| 58% | NAOMIEHARRIS | 12 | Actress who played Chiron's biological mother Paula in "Moonlight": 2 wds. |
| 56% | SALLYHAWKINS | 12 | "The Shape of Water" actress who plays Willy Wonka's mother in "Wonka": 2 wds. |
| 56% | LESLIEJONES | 11 | Actress who plays the mother of Prince Akeem's son in "Coming 2 America": 2 wds. |
| 55% | EVALONGORIA | 11 | "Overboard" actress who plays Dora's mother in "Dora and the Lost City of Gold": 2 wds. |
| 54% | LESLIEJONES | 11 | "Ghostbusters" actress who plays the mother of Prince Akeem's son in "Coming 2 America": 2 wds. |
| 54% | FRANCESFISHER | 13 | Actress who played Ruth DeWitt Bukater, Rose's widowed mother in the movie "Titanic": 2 wds. |
| 54% | PIPERLAURIE | 11 | "Carrie" actress who played 27-Across's mother in "Children of a Lesser God": 2 wds. |
| 53% | ANGELABASSETT | 13 | Actress who plays the queen mother of Wakanda in "Black Panther": 2 wds. |
| 53% | KATIEFINNERAN | 13 | "Bloodline" and "Brockmire" actress who plays Millie's mother in "Freaky" (2 wds.) |
| 53% | MARISATOMEI | 11 | "My Cousin Vinny" actress who plays 30-Across's mother in "The King of Staten Island": 2 wds. |
| 53% | SALLYHAWKINS | 12 | "The Shape of Water" actress who plays Wonka's mother in "Wonka" (2 wds.) |
| 53% | DIANNEWIEST | 11 | "The Mule" actress who played Sam and Michael's mother Lucy in "The Lost Boys": 2 wds. |
| 52% | EMILYMITCHELL | 13 | "Women Talking" actress who plays Elivs Presley's daughter in "Priscilla" (2 wds.) |
| 52% | RENERUSSO | 9 | Actress who played Thor's mother Frigga: 2 wds. |
| 52% | SUSANSARANDON | 13 | 18-Across and 43-Across actress who plays Carla's mother in "A Bad Moms Christmas" (2 wds.) |
| 51% | EMMYROSSUM | 10 | "Shameless" actress who plays Danny's mother on "The Crowded Room": 2 wds. |
| 51% | JANETLEIGH | 10 | "Psycho" actress who played Rosie DeLeon in 30-Across: 2 wds. |
| 51% | JUNESQUIBB | 10 | Actress who plays Woody's wife Kate in "Nebraska": 2 wds. |
| 51% | LAURALINNEY | 11 | Actress who played an assistant district attorney in 1996's "Primal Fear": 2 wds. |
| 51% | KELLYMCGILLIS | 13 | Actress who played an assistant district attorney in 1988's "The Accused": 2 wds. |
| 51% | KATIEHOLMES | 11 | Actress who played an assistant district attorney in 2005's "Batman Begins": 2 wds. |
| 51% | POLLYBERGEN | 11 | "The Caretakers" actress who played Sam's wife Peggy in "Cape Fear": 2 wds. |
| 51% | JANELLEMONAE | 12 | Actress who played Chiron's maternal figure Teresa in "Moonlight": 2 wds. |
| 51% | JENNIFERLOPEZ | 13 | "Selena" singer and actress who plays an ex-assassin in the new movie "The Mother": 2 wds. |
| 51% | SALMAHAYEK | 10 | "Frida" actress who plays an assassin's wife in "The Hitman's Bodyguard": 2 wds. |
| 51% | JOHNTRAVOLTA | 12 | "Grease" actor who played James Ubriacco in "Look Who's Talking": 2 wds. |
| 51% | JULIAROBERTS | 12 | "Pretty Woman" actress who played young mother Shelby in "Steel Magnolias": 2 wds. |
| 50% | CONNIENIELSEN | 13 | "Gladiator" actress who plays Diana's mother, Queen Hippolyta: 2 wds. |