| 100% | ORM | 3 | "N ___?" (Agatha Christie novel) |
| 93% | THEN | 4 | Agatha Christie novel "And ___ There Were None" |
| 93% | ORIENT | 6 | Agatha Christie novel "Murder on the ___ Express" |
| 91% | NILE | 4 | Setting for an Agatha Christie novel |
| 91% | WERENONE | 8 | And Then There __, Agatha Christie novel |
| 89% | POISON | 6 | Downfall in many an Agatha Christie novel |
| 89% | RYE | 3 | "A Pocket Full of ___," Agatha Christie novel |
| 89% | NILE | 4 | Death scene in an Agatha Christie novel |
| 88% | CLOCKS | 6 | The —, 1963 Agatha Christie novel featuring Hercule Poirot |
| 88% | MURDER | 6 | Crime named in nine Agatha Christie novel titles |
| 88% | MIRRORS | 7 | They Do It With __, 1952 Agatha Christie novel |
| 88% | AFTER | 5 | & 6D 1953 Agatha Christie novel featuring Hercule Poirot |
| 88% | ACARIBBEAN | 10 | & 16D 1964 Agatha Christie novel featuring Miss Marple |
| 88% | POISONPOWDER | 12 | Means of murder in some Agatha Christie novels |
| 88% | COLLINS | 7 | Original publisher of nearly all Agatha Christie novels |
| 86% | BAGHDAD | 7 | They Came to __, Agatha Christie novel set in Iraq |
| 86% | NORM | 4 | 1941 Agatha Christie novel featuring Tommy and Tuppence Beresford |
| 86% | BROWNSUIT | 9 | Man in the __, Agatha Christie novel set in Africa |
| 86% | CURTAIN | 7 | 1975 Agatha Christie novel subtitled Poirot's Last Case |
| 86% | DEADMANSFOLLY | 13 | 1956 Agatha Christie novel featuring 30-Across (3 wds.) |
| 86% | THEABCMURDERS | 13 | 1936 Agatha Christie novel featuring 30-Across (3 wds.) |
| 86% | VICARAGE | 8 | Agatha Christie mystery novel: Murder at the __ |
| 83% | HERCULEPOIROT | 13 | Belgian detective who appears in 33 Agatha Christie novels (2 wds.) |
| 83% | ORIENTEXPRESS | 13 | Train in an Agatha Christie detective novel |
| 82% | NILE | 4 | "Death on the ___" (Kenneth Branagh film based on an Agatha Christie novel) |
| 77% | ORM | 3 | Agatha Christie's "N___?" |
| 77% | ORM | 3 | Agatha Christie's "N ___?" |
| 76% | WESTMACOTT | 10 | Mary —, pseudonym under which Agatha Christie wrote 1930 novel Giant's Bread |
| 74% | NILE | 4 | "Death on the ___" (Agatha Christie novel) |