| 100% | JULIANMCMAHON | 13 | "Nip/Tuck" actor who plays Supervisory Special Agent Jess LaCroix on "FBI: Most Wanted" (2 wds.) |
| 54% | KYLEMACLACHLAN | 14 | "Portlandia" actor who played FBI Special Agent Dale Cooper on "Twin Peaks": 2 wds. |
| 52% | LUKEKLEINTANK | 13 | "The Man in the High Castle" actor who plays Supervisory Special Agent Scott Forrester on "FBI: International" (2 wds.) |
| 50% | KEVINBACON | 10 | Actor who plays an FBI special agent in "Black Mass": 2 wds. |
| 47% | KEVINBACON | 10 | "The Following" actor who plays FBI agent Jackie Rohr on Showtime's "City on a Hill": 2 wds. |
| 47% | DYLANMCDERMOTT | 14 | "The Practice" actor who plays team leader Remy Scott on CBS's "FBI: Most Wanted": 2 wds. |
| 47% | JULIANMCMAHON | 13 | "Nip/Tuck" actor who stars as Jess LaCroix on 18-Across: 2 wds. |
| 46% | ZEEKOZAKI | 9 | "Valor" actor who plays agent O.A. Zidan on "FBI": 2 wds. |
| 46% | KALPENN | 7 | "Designated Survivor" actor who plays an FBI agent on 34-Across (2 wds.) |
| 46% | MARKHARMON | 10 | "Chicago Hope" actor who plays Special Agent Leroy Gibbs on "NCIS": 2 wds. |
| 45% | CHRISODONNELL | 13 | "Grey's Anatomy" actor who plays Special Agent G. Callen on "NCIS: Los Angeles": 2 wds. |
| 45% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title GBI special agent on 50-Across (2 wds.) |
| 45% | LUCASBLACK | 10 | "American Gothic" actor who plays Special Agent Christopher Lasalle on "NCIS: New Orleans": 2 wds. |
| 44% | DONADAMS | 8 | Actor who played Agent 86 on 16-Across: 2 wds. |
| 43% | TIMOTHYSIMONS | 13 | "Veep" actor who plays Sasha on "Nobody Wants This": 2 wds. |
| 42% | TYRESEGIBSON | 12 | "The Fate of the Furious" actor who plays FBI agent Simon Stroud in "Morbius": 2 wds. |
| 42% | OMARIHARDWICK | 13 | "Army of the Dead" actor who plays an FBI agent in "The Mother": 2 wds. |
| 42% | JACKLOWDEN | 10 | "Dunkirk" actor who plays up-and-coming agent River Cartwright on "Slow Horses": 2 wds. |
| 42% | JEREMYSISTO | 11 | "Law & Order" actor who plays agent Jubal Valentine on "FBI": 2 wds. |
| 41% | JEREMYSISTO | 11 | "Law & Order" actor who plays agent Jubal Valentine on the new CBS crime drama "FBI" (2 wds.) |
| 41% | KYLESCHMID | 10 | "Six" actor who plays an NIS agent on "NCIS: Origins": 2 wds. |
| 41% | GARYBUSEY | 9 | "The Buddy Holly Story" actor who played FBI agent Angelo Pappas in 1991's "Point Break": 2 wds. |
| 40% | MARTINFREEMAN | 13 | "Sherlock" actor who plays former CIA agent Everett Ross on "Secret Invasion": 2 wds. |
| 40% | CLIVEOWEN | 9 | "Closer" actor who plays FBI agent Montgomery in "The Informer" (2 wds.) |
| 40% | MARKHARMON | 10 | Former "Chicago Hope" actor who plays agent Gibbs on "NCIS" (2 wds.) |
| 40% | KYLEMACLACHLAN | 14 | Actor who is known for playing Special Agent Dale Cooper in the cult TV series "Twin Peaks": 2 wds. |
| 39% | JAMESSPADER | 11 | "Boston Legal" actor who plays FBI informant Red Reddington on 27-Across (2 wds.) |
| 39% | HARRYLENNIX | 11 | "Billions" actor who plays FBI assistant director Harold Cooper on 27-Across (2 wds.) |
| 39% | CHRISODONNELL | 13 | Former "Grey's Anatomy" actor who plays agent Callan on "NCIS: Los Angeles" (2 wds.) |
| 39% | BILLYPORTER | 11 | Actor who plays Pray Tell on "Pose": 2 wds. |