| 100% | LAURENGRAHAM | 12 | "Parenthood" actress who played mother Lorelai on 14-Across: 2 wds. |
| 61% | RUBYROSE | 8 | "Orange Is the New Black" actress who plays Kate Kane on 14-Across: 2 wds. |
| 61% | QUEENLATIFAH | 12 | "Girls Trip" actress who plays vigilante Robyn McCall on 14-Across: 2 wds. |
| 60% | SUSANCLARK | 10 | Actress who played the adoptive mother on the 1980s sitcom "Webster": 2 wds. |
| 60% | CONSTANCEWU | 11 | Actress who plays 36-Across's mother on "Fresh off the Boat" (2 wds.) |
| 59% | ALEXISBLEDEL | 12 | "The Sisterhood of the Traveling Pants" actress who played daughter Rory on 14-Across: 2 wds. |
| 59% | EMMYROSSUM | 10 | "Shameless" actress who plays Danny's mother on "The Crowded Room": 2 wds. |
| 59% | BARBARAFELDON | 13 | Actress who played Agent 99 on 16-Across: 2 wds. |
| 59% | DANIELLEFISHEL | 14 | Actress who plays Topanga Matthews on 33-Across: 2 wds. |
| 58% | CARRIEFISHER | 12 | Actress who played 14-Across: 2 wds. |
| 58% | KATEMARA | 8 | "House of Cards" actress who plays high school instructor Claire Wilson on 14-Across: 2 wds. |
| 57% | MAEWHITMAN | 10 | "Parenthood" actress who plays Annie Marks on "Good Girls": 2 wds. |
| 57% | SARAHCHALKE | 11 | "Scrubs" actress who plays Kate Mularkey on 19-Across: 2 wds. |
| 57% | KATHERINEHEIGL | 14 | "Suits" actress who plays Tully Hart on 19-Across: 2 wds. |
| 57% | LAURENGRAHAM | 12 | Actress who played Sarah Braverman on "Parenthood": 2 wds. |
| 56% | BLYTHEDANNER | 12 | Actress who plays Will Truman's mother on "Will & Grace" (2 wds.) |
| 56% | REBELWILSON | 11 | "Bridesmaids" actress who played Fat Amy in 14-Across: 2 wds. |
| 56% | ISABELSANFORD | 13 | Actress who played Louise on 15-Across: 2 wds. |
| 55% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 55% | COURTENEYCOX | 12 | Actress who played Monica Geller on 29-Across (2 wds.) |
| 55% | SALLYSTRUTHERS | 14 | Actress who played Gloria Stivic on 56-Across (2 wds.) |
| 55% | LAWANDAPAGE | 11 | Actress who played Aunt Esther on 29-Across (2 wds.) |
| 55% | ISABELLAGOMEZ | 13 | Actress who plays Elena Alvarez on 49-Across (2 wds.) |
| 55% | PAGETBREWSTER | 13 | Actress who plays Emily Prentiss on 47-Across (2 wds.) |
| 55% | LUCYLIU | 7 | Actress who played Joan (based on 47-Across) on the CBS series "Elementary": 2 wds. |
| 54% | NAOMIWATTS | 10 | "King Kong" actress who plays wife Nora on 16-Across: 2 wds. |
| 54% | ZOSIAMAMET | 10 | Actress who plays Shoshanna on "Girls": 2 wds. |
| 54% | LAURIEMETCALF | 13 | "The Conners" actress who played Sheldon's mother on "The Big Bang Theory" (2 wds.) |
| 54% | JESSICAWALTER | 13 | "Archer" actress who played Michael Bluth's mother Lucille on "Arrested Development": 2 wds. |
| 54% | MOLLYSHANNON | 12 | "Divorce" actress who plays the mother of the siblings on 36-Across (2 wds.) |