| 100% | LETITIAWRIGHT | 13 | "Ready Player One" actress who plays Shuri in 44-Across (2 wds.) |
| 70% | OLIVIACOOKE | 11 | "Ready Player One" actress who plays the pregnant girlfriend of a murdered man in 31-Across (2 wds.) |
| 66% | OLIVIACOOKE | 11 | "Bates Motel" actress who plays Art3mis in "Ready Player One" (2 wds.) |
| 63% | PERDITAWEEKS | 12 | "Ready Player One" actress who played Juliet Higgins on "Magnum P.I.": 2 wds. |
| 62% | EVANOBLEZADA | 12 | "Luck" voice actress who plays Ruth in 44-Across (2 wds.) |
| 62% | LETITIAWRIGHT | 13 | Actress who plays Shuri in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 62% | LETITIAWRIGHT | 13 | "Death on the Nile" actress who plays Shuri in "Black Panther: Wakanda Forever": 2 wds. |
| 60% | AMYBRENNEMAN | 12 | Former "NYPD Blue" actress who plays Laurie Garvey in 44-Across: 2 wds. |
| 59% | BRIELARSON | 10 | "Room" actress who plays 44-Across in "Captain Marvel" (2 wds.) |
| 59% | LUPITANYONGO | 12 | "12 Years a Slave" actress who plays Nakia in 44-Across (2 wds.) |
| 58% | RACHELMCADAMS | 13 | "Spotlight" actress who played Allie Hamilton in 44-Across (2 wds.) |
| 58% | LETITIAWRIGHT | 13 | "Death on the Nile" actress who plays Shuri in "Black Panther: Wakanda Forever" (2 wds.) |
| 58% | GLENNCLOSE | 10 | "Hillbilly Elegy" actress who played Vice President Kathryn Bennett in "Air Force One": 2 wds. |
| 57% | LETITIAWRIGHT | 13 | "Death on the Nile" actress who plays Shuri in the Marvel film "Black Panther" (2 wds.) |
| 57% | MCKENNAGRACE | 12 | "The Haunting of Hill House" actress who plays young 44-Across in "Captain Marvel" (2 wds.) |
| 57% | ELLIEKEMPER | 11 | Actress who plays the lead role in 12-/24-Across: 2 wds. |
| 57% | MAYARUDOLPH | 11 | "Bridesmaids" actress who plays Christine in 32-Across: 2 wds. |
| 57% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 56% | CRISTINMILIOTI | 14 | Actress who plays a wedding guest who's stuck in a time loop in 44-Across: 2 wds. |
| 56% | ELLENBARKIN | 11 | "Sea of Love" actress who plays Smurf Cody in 44-Across (2 wds.) |
| 56% | JULIANNEMOORE | 13 | "Still Alice" actress who plays 19-Across later in life: 2 wds. |
| 56% | RACHELZEGLER | 12 | Actress who plays Maria in 30-Across (2 wds.) |
| 56% | ARIANADEBOSE | 12 | Actress who plays Anita in 30-Across (2 wds.) |
| 55% | FELICITYJONES | 13 | Actress who plays criminal-turned-Rebel Jyn Erso in "Rogue One" (2 wds.) |
| 55% | MIREILLEENOS | 12 | "The Killing" actress who plays Marissa in 33-Across: 2 wds. |
| 55% | JACKIWEAVER | 11 | "Silver Linings Playbook" actress who plays Sandy in 32-Across: 2 wds. |
| 55% | SANDRADEE | 9 | Actress who played Gidget in 1959: 2 wds. |
| 54% | BENMENDELSOHN | 13 | "Ready Player One" actor who plays Skrull leader Talos on "Secret Invasion": 2 wds. |
| 54% | LETITIAWRIGHT | 13 | "Avengers: Endgame" actress who played technology expert Shuri in "Black Panther": 2 wds. |
| 54% | ROXIEROKER | 10 | Actress who played Helen Willis, the friendly neighbor in the '70s sitcom "The Jeffersons" which is one of the longest-running sitcoms: 2 wds. |