| 100% | TARONEGERTON | 12 | "Rocketman" actor who plays James Keene in 46-Across (2 wds.) |
| 69% | RAYLIOTTA | 9 | "Goodfellas" actor who plays James "Big Jim" Keene on 46-Across (2 wds.) |
| 67% | CHRISTIANKANE | 13 | "Leverage" actor who plays Jacob Stone in 46-Across (2 wds.) |
| 64% | DANIELCRAIG | 11 | "Knives Out" actor who plays James Bond in 39-Across (2 wds.) |
| 62% | JOHNTRAVOLTA | 12 | "Grease" actor who played James Ubriacco in "Look Who's Talking": 2 wds. |
| 62% | TOMHOLLAND | 10 | Actor who plays Spider-Man in 16-Across: 2 wds. |
| 62% | JOSHBROLIN | 10 | Actor who plays the fixer in 18-Across: 2 wds. |
| 62% | BRUCEWILLIS | 11 | Actor who played David Dunn in 38-Across: 2 wds. |
| 62% | JACKIEGLEASON | 13 | Actor who played Minnesota Fats in 18-Across: 2 wds. |
| 61% | HARRISONFORD | 12 | "Blade Runner" actor who played President James Marshall in "Air Force One": 2 wds. |
| 61% | ROYSCHEIDER | 11 | "Jaws" actor who played "Doc" Levy in 18-Across: 2 wds. |
| 61% | ALECGUINNESS | 12 | Oscar-winning actor who played 46-Across in the original "Star Wars" trilogy (2 wds.) |
| 61% | JOHNNYDEPP | 10 | Actor who plays 26-/37-Across in "Black Mass": 2 wds. |
| 60% | ERICBANA | 8 | Actor who played 32-Across in a 2003 film: 2 wds. |
| 60% | EDWARDNORTON | 12 | Actor who played 32-Across in a 2008 film: 2 wds. |
| 60% | CHRISPINE | 9 | Actor who plays James T. Kirk in the "Star Trek" reboot films (2 wds.) |
| 60% | JAMESMCAVOY | 11 | "His Dark Materials" actor who plays Paddy in 46-Across (2 wds.) |
| 59% | JONAHHILL | 9 | "Moneyball" actor who plays himself in 30-/32-Across: 2 wds. |
| 59% | JAMIEFOXX | 9 | "Ray" actor who plays Little John in 16-Across: 2 wds. |
| 59% | TOMHANKS | 8 | "Big" actor who played Ray Peterson in 50-Across: 2 wds. |
| 59% | GENEWILDER | 10 | Actor who played 31-/34-Across in a 1971 film: 2 wds. |
| 59% | JOHNNYDEPP | 10 | Actor who played 31-/34-Across in a 2005 film: 2 wds. |
| 59% | DUSTINHOFFMAN | 13 | "Rain Man" actor who played "Babe" Levy in 18-Across: 2 wds. |
| 59% | LEEJ | 4 | Actor Cobb who plays James Coburn's former boss in "Our Man Flint": 2 wds. |
| 58% | EWANMCGREGOR | 12 | Actor who played 29-/32-Across in the 1990s and 2000s: 2 wds. |
| 58% | ALECGUINNESS | 12 | Actor who played 29-/32-Across in the 1970s and 1980s: 2 wds. |
| 58% | JASONMOMOA | 10 | Actor who plays Aquaman in 30-Across: 2 wds. |
| 58% | BENAFFLECK | 10 | Actor who plays Batman in 30-Across: 2 wds. |
| 58% | NICOLASCAGE | 11 | "Leaving Las Vegas" actor who played "Hi" McDunnough in 32-Across: 2 wds. |
| 58% | SETHROGEN | 9 | "Knocked Up" actor who plays himself in 30-/32-Across: 2 wds. |