| 100% | JOHNTRAVOLTA | 12 | "Saturday Night Fever" actor who reportedly passed on the "Forrest Gump" role that went to Tom Hanks: 2 wds. |
| 57% | MOLLYRINGWALD | 13 | "Pretty in Pink" actress who reportedly passed on the "Pretty Woman" role that went to Julia Roberts: 2 wds. |
| 57% | HARRISONFORD | 12 | "Raiders of the Lost Ark" actor who reportedly passed on the "Schindler's List" role that went to Liam Neeson: 2 wds. |
| 35% | NOAHMILLS | 9 | Actor who learned to do some suturing for his role as a combat medic on NBC's "The Brave": 2 wds. |
| 35% | JOHNTRAVOLTA | 12 | "Saturday Night Fever" actor who played hit man Vincent Vega in the 1994 film "Pulp Fiction" (2 wds.) |
| 34% | SUMMERSIXTEEN | 13 | 2016 Drake hit that went to #1 on the Billboard R&B and Rap charts: 2 wds. |
| 34% | HOTLINEBLING | 12 | 2015 Drake hit that went to #1 on the Billboard R&B and Rap charts: 2 wds. |
| 34% | BOBODENKIRK | 11 | "Breaking Bad" actor who plays the lead role on 33-Across: 2 wds. |
| 34% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 33% | JOHNTRAVOLTA | 12 | "Saturday Night Fever" actor who played criminal Vincent Vega in "Pulp Fiction": 2 wds. |
| 33% | LIEVSCHREIBER | 13 | "Spotlight" actor who has been nominated for three Emmys for playing the title role on 43-Across: 2 wds. |
| 33% | TIMROTH | 7 | "Pulp Fiction" actor who played Dr. Cal Lightman on the Fox series "Lie To Me": 2 wds. |
| 32% | PAULGIAMATTI | 12 | "Cinderella Man" and "Sideways" actor who turned down the role of Michael Scott on "The Office": 2 wds. |
| 32% | BILLHADER | 9 | Former "Saturday Night Live" cast member who plays the title role on 4-Across (2 wds.) |
| 32% | JONATHANGROFF | 13 | Actor who originated the role of 15-Across on Broadway (2 wds.) |
| 32% | SHEMARMOORE | 11 | "S.W.A.T." actor who won an Emmy for his role on "The Young and the Restless": 2 wds. |
| 32% | LAMORNEMORRIS | 13 | "New Girl" actor who plays cartoonist Keef Knight, newly attuned to racial injustice, on the Hulu comedy "Woke": 2 wds. |
| 32% | ASHTONKUTCHER | 13 | "That '70s Show" actor who has been played by 17-Across on "Saturday Night Live": 2 wds. |
| 31% | TARANKILLAM | 11 | Actor who plays 19th-century newspaper critic Jebidiah Atkinson on "Saturday Night Live": 2 wds. |
| 31% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 31% | PATRICKSTEWART | 14 | "X-Men" actor who plays the title role on 50-Across (2 wds.) |
| 31% | KENNETHCHOI | 11 | Actor who played Chester Ming on "The Wolf of Wall Street" and portrays the role of Judge Lance Ito in "American Crime Story" : 2 wds. |
| 31% | ALANRITCHSON | 12 | "Titans" actor who plays the title role on the Amazon series "Reacher" (2 wds.) |
| 31% | TOPHERGRACE | 11 | Actor who played the role of Eric Forman in the TV show "That '70s Show": 2 wds. |
| 31% | TAYLORKITSCH | 12 | "Friday Night Lights" actor who plays Paul Woodrugh on the latest season of "True Detective": 2 wds. |
| 31% | MATTDAMON | 9 | "The Martian" actor who went bald for his role in "Elysium": 2 wds. |
| 31% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role on "Perry Mason" (2 wds.) |
| 31% | ALECBALDWIN | 11 | Actor who made a cameo in "Glengarry Glen Ross" by playing the role of Blake, the guy who is sent to motivate the sales team: 2 wds. |
| 30% | ALEXKARRAS | 10 | Actor who played the adoptive father on "Webster": 2 wds. |
| 30% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |